Structural characterization of reverse transcriptase and endonuclease polypeptides of the acquired immunodeficiency syndrome retrovirus.
about
Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates.HIV-1 reverse transcriptionStructural basis for activation of α-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptaseComplexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradationAnti-(human immunodeficiency virus) activity of polyoxotungstates and their inhibition of human immunodeficiency virus reverse transcriptaseMechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosineNewly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase HConservation patterns of HIV-1 RT connection and RNase H domains: identification of new mutations in NRTI-treated patientsNucleotide sequence and genomic organization of feline immunodeficiency virus.Mutational sensitivity patterns define critical residues in the palm subdomain of the reverse transcriptase of human immunodeficiency virus type 1.Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles.Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants.A single amino acid substitution in HIV-1 reverse transcriptase significantly reduces virion release.Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activityLinker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain.HIV-1 replication is controlled at the level of T cell activation and proviral integration.AIDS virus reverse transcriptase defined by high level expression in Escherichia coli.Domain structure of the human immunodeficiency virus reverse transcriptase.Rigorous assessment and integration of the sequence and structure based features to predict hot spots.Anti-human immunodeficiency virus type 1 activity of novel 6-substituted 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives.Placement of leucine zipper motifs at the carboxyl terminus of HIV-1 protease significantly reduces virion production.Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.Identification and characterization of HIV-specific RNase H by monoclonal antibody.Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo.Substitution of a highly basic helix/loop sequence into the RNase H domain of human immunodeficiency virus reverse transcriptase restores its Mn(2+)-dependent RNase H activity.HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'----5' exonuclease activityRelationship between plus strand DNA synthesis removal of downstream segments of RNA by human immunodeficiency virus, murine leukemia virus and avian myeloblastoma virus reverse transcriptasesRelocation of a protease-like gene segment between two retrovirusesLeukodepletion as a point-of-care method for monitoring HIV-1 viral load in whole blood.Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replicationExpression of human immunodeficiency virus type 1 reverse transcriptase in trans during virion release and after infection.Subunit-specific mutagenesis of the cysteine 280 residue of the reverse transcriptase of human immunodeficiency virus type 1: effects on sensitivity to a specific inhibitor of the RNase H activity.Inhibition of the p66/p51 form of human immunodeficiency virus reverse transcriptase by tRNA(Lys)A positively charged side chain at position 154 on the beta8-alphaE loop of HIV-1 RT is required for stable ternary complex formation.Human immunodeficiency virus-1 reverse transcriptase heterodimer stability.Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytesBinding of RNA template to a complex of HIV-1 reverse transcriptase/primer/templateContributions of DNA polymerase subdomains to the RNase H activity of human immunodeficiency virus type 1 reverse transcriptasePurification and characterization of an active human immunodeficiency virus type 1 RNase H domain.Phosphorylation of the avian retrovirus integration protein and proteolytic processing of its carboxyl terminus.
P2860
Q24812175-CFCD5C45-EF18-476B-82CC-B15F32BD7D3FQ27023387-723282AC-2011-4715-91C9-333B5C5D74A0Q27625384-208EBBBB-C90F-4E84-B175-2805A00D2E51Q27675888-34871A71-84B8-431C-8879-594AAFC7E4E6Q28367667-958780CB-8AA9-4C18-9D8D-806F9846F089Q28368041-02990F03-25DC-42BF-9069-52EC0DC63BC2Q28469134-46B3DD11-A237-4D1F-B156-2FD2A5FB5A12Q28472255-2E531248-8E36-41C7-B755-DA2267FF5E67Q30011272-50328004-79E4-4AB6-B958-533684F34F61Q30416860-61B69F1E-4006-4255-8771-407A48EA6D5AQ30452154-18CE35EE-8CF4-45BF-8DF6-32F9783537DBQ33554232-6251C466-AC0E-4A84-9A75-94C2FDF00273Q33558367-D8C5C143-5188-4C0D-932E-F38077F81202Q33666234-B6EDA512-8EB9-4928-A38D-EDF97D001AADQ33852475-78EE1785-208D-4FF8-9F03-5D7991145C76Q33919765-8CDAD101-E753-473B-888E-69C9B85521F4Q33929729-12C4F6C9-9CD7-44F2-AF5A-70559E02888CQ33937534-1E459734-F4F1-44FB-9084-C55F45B1BFF0Q33974356-4FB5C685-3F0E-4554-8988-D0C2785216D6Q34145448-6D9374D5-76F4-449A-82E7-780378E2A328Q34187294-DE4E85D7-3EB4-4F5A-A3A2-8B6DE9582AF6Q34320065-CE59525F-55DC-4E47-B298-7570FDA7980DQ34403789-2466A70E-F7B7-4356-94BD-A0D3749DFD73Q34438247-C3C55D5D-243F-4BCD-BE74-5C6000BEE68DQ34498422-549E8C78-D1D3-4105-A354-96ED484B8B09Q34557590-F14A3A1E-69C0-4A64-8AF4-793CC0A910BAQ34595077-7DC40B92-4C76-4854-BB9D-B7315B786B2BQ34617236-7EB350FD-9517-434F-9AA0-476C9C238679Q35193276-1646D093-FB91-4E8C-8BB8-356F4C23425CQ35838477-A949FE38-B005-4415-A96B-EDD280E45DF2Q35861729-7F2B2E9E-5514-418F-A979-82060D7219D6Q35889066-51BDC13C-F347-4C95-AFAE-A00B6A9774F8Q35907165-5A9FE3E1-1683-4092-A3A0-5C9A3E7DCB3AQ36247837-21FC3198-04D4-45E2-BD2A-71C754B2D0A7Q36278833-86FB9FFA-6B79-496C-96F3-5553B0BA2082Q36354762-F8C4B2C5-FD5D-4AEE-B2EC-096C0DAE6152Q36591740-0D15A0B0-3CC0-48AF-A408-8B3C52D48901Q36635062-4FF3EA0C-C0D3-4D6B-A7EA-74E2144AC4DDQ36650031-7B4119FB-2B95-4EA2-889A-B4CEB99E1B60Q36681557-FBFAE998-279C-4AEE-97DB-74B6F4C3C6B2
P2860
Structural characterization of reverse transcriptase and endonuclease polypeptides of the acquired immunodeficiency syndrome retrovirus.
description
1986 nî lūn-bûn
@nan
1986 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Structural characterization of ...... eficiency syndrome retrovirus.
@ast
Structural characterization of ...... eficiency syndrome retrovirus.
@en
type
label
Structural characterization of ...... eficiency syndrome retrovirus.
@ast
Structural characterization of ...... eficiency syndrome retrovirus.
@en
prefLabel
Structural characterization of ...... eficiency syndrome retrovirus.
@ast
Structural characterization of ...... eficiency syndrome retrovirus.
@en
P2093
P2860
P1433
P1476
Structural characterization of ...... eficiency syndrome retrovirus.
@en
P2093
Coligan JE
Lightfoote MM
Venkatesan S
P2860
P304
P407
P577
1986-11-01T00:00:00Z