HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'----5' exonuclease activity
about
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNATwo-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitorsRNase H activity: structure, specificity, and function in reverse transcriptionRibonuclease H: properties, substrate specificity and roles in retroviral reverse transcriptionHIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors.Secondary structure and hybridization accessibility of hepatitis C virus 3'-terminal sequences.Influence of the RNase H domain of retroviral reverse transcriptases on the metal specificity and substrate selection of their polymerase domainsCrystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNACombinatorial selection, inhibition, and antiviral activity of DNA thioaptamers targeting the RNase H domain of HIV-1 reverse transcriptaseHuman immunodeficiency virus type 1 stimulates the expression and production of secretory leukocyte protease inhibitor (SLPI) in oral epithelial cells: a role for SLPI in innate mucosal immunityRelative rates of retroviral reverse transcriptase template switching during RNA- and DNA-dependent DNA synthesis.Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.Domain structure of the human immunodeficiency virus reverse transcriptase.Sequence, distance, and accessibility are determinants of 5'-end-directed cleavages by retroviral RNases H.Relationship between plus strand DNA synthesis removal of downstream segments of RNA by human immunodeficiency virus, murine leukemia virus and avian myeloblastoma virus reverse transcriptasesIntensity of deoxycytidine deamination of HIV-1 proviral DNA by the retroviral restriction factor APOBEC3G is mediated by the noncatalytic domain.Compensation by the E138K mutation in HIV-1 reverse transcriptase for deficits in viral replication capacity and enzyme processivity associated with the M184I/V mutations.Effects on DNA synthesis and translocation caused by mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptaseDetection of an RNase H activity associated with hepadnaviruses.Sequence and structural determinants required for priming of plus-strand DNA synthesis by the human immunodeficiency virus type 1 polypurine tract.RNase H domain of Moloney murine leukemia virus reverse transcriptase retains activity but requires the polymerase domain for specificity.Sequence-independent RNA cleavages generate the primers for plus strand DNA synthesis in hepatitis B viruses: implications for other reverse transcribing elements.Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template.primer complexes.Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivoWhen retroviral reverse transcriptases reach the end of their RNA templates.Double-stranded RNA-dependent RNase activity associated with human immunodeficiency virus type 1 reverse transcriptase.The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase.Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activitiesReconstitution in vitro of RNase H activity by using purified N-terminal and C-terminal domains of human immunodeficiency virus type 1 reverse transcriptase.The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activityHIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNAMixed backbone antisense oligonucleotides: design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments.RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA).Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptasesSequence requirements for removal of tRNA by an isolated human immunodeficiency virus type 1 RNase H domainRequirements for minus-strand transfer catalyzed by Rous sarcoma virus reverse transcriptase.Purification and enzymatic characterization of the hepatitis B virus ribonuclease H, a new target for antiviral inhibitors.Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides.Cross-packaging of genetically distinct mouse and primate retroviral RNAs.Long terminal repeat enhancer core sequences in proviruses adjacent to c-myc in T-cell lymphomas induced by a murine retrovirus.
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P2860
HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'----5' exonuclease activity
description
1990 nî lūn-bûn
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1990 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@ast
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@en
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@nl
type
label
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@ast
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@en
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@nl
prefLabel
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@ast
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@en
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@nl
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P1433
P1476
HIV-1 RT-associated ribonuclea ...... 3'----5' exonuclease activity
@en
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P304
P407
P577
1990-04-01T00:00:00Z