Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes. - Wikidata - wikimedia - TriplyDB

Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

http://www.wikidata.org/entity/Q33930262

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Genes involved in pancreatic islet cell rejuvenation Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells.Natural history of β-cell adaptation and failure in type 2 diabetes β-Cell regeneration mediated by human bone marrow mesenchymal stem cells.The beneficial effects of combined grape pomace and omija fruit extracts on hyperglycemia, adiposity and hepatic steatosis in db/db mice: a comparison with major index compounds Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway.Type 2 diabetes and the aging pancreatic beta cell.Preserving Mafa expression in diabetic islet β-cells improves glycemic control in vivo GPR43 Potentiates β-Cell Function in Obesity.Aldosterone induces clonal β-cell failure through glucocorticoid receptor.Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells.Inactivation of specific β cell transcription factors in type 2 diabetes.Thioredoxin-interacting protein regulates insulin transcription through microRNA-204 MafA and MafB activity in pancreatic β cells.Involvement of oxidative stress in suppression of insulin biosynthesis under diabetic conditions.Reactive aldehydes--second messengers of free radicals in diabetes mellitus.Down-regulation of pancreatic transcription factors and incretin receptors in type 2 diabetes.Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls β, α, and δ-cell masses in genetic obese mice.Role of pancreatic transcription factors in maintenance of mature β-cell function.Appropriate therapy for type 2 diabetes mellitus in view of pancreatic β-cell glucose toxicity: "the earlier, the better".A novel function of Onecut1 protein as a negative regulator of MafA gene expression.All mixed up: defining roles for β-cell subtypes in mature islets.Activation of PPARδ up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate.Is β-cell aging involved in the pathogenesis of diabetes?Characterization of age-associated alterations of islet function and structure in diabetic mutant cryptochrome 1 transgenic mice.How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?Repression of COUP-TFI Improves Bone Marrow-Derived Mesenchymal Stem Cell Differentiation into Insulin-Producing Cells.A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes.Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells Into β-Cells In Vivo.Optical clearing of the pancreas for visualization of mature β-cells and vessels in mice.MafA is critical for maintenance of the mature beta cell phenotype in mice.Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

http://www.wikidata.org/entity/Q33930262

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.

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Hideaki Kaneto

http://www.w3.org/2001/XMLSchema#string

Iichiro Shimomura

http://www.w3.org/2001/XMLSchema#string

Kaoru Yamamoto

http://www.w3.org/2001/XMLSchema#string

Ken Kato

http://www.w3.org/2001/XMLSchema#string

Munehide Matsuhisa

http://www.w3.org/2001/XMLSchema#string

Roland Stein

http://www.w3.org/2001/XMLSchema#string

Taka-aki Matsuoka

http://www.w3.org/2001/XMLSchema#string

Takeshi Miyatsuka

http://www.w3.org/2001/XMLSchema#string

Tsunehiko Yamamoto

http://www.w3.org/2001/XMLSchema#string

P2860

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

Phosphorylation of MafA is essential for its transcriptional and biological properties

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

A simplified system for generating recombinant adenoviruses

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

MafA is a key regulator of glucose-stimulated insulin secretion.

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10.2337/DB08-0693

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7

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59

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2010-04-27T00:00:00Z

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43348383

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20424231

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2889771

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