Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. - Wikidata - wikimedia - TriplyDB

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

http://www.wikidata.org/entity/Q24531243

about

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription The MafA transcription factor appears to be responsible for tissue-specific expression of insulin Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus Genes involved in pancreatic islet cell rejuvenation Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells Extracellular matrix modulates insulin production during differentiation of AR42J cells: functional role of Pax6 transcription factor Role of the mitogen-activated protein kinases in cytokine-mediated inhibition of insulin gene expression The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells Regulation of the insulin gene by glucose and fatty acids Integrating human omics data to prioritize candidate genes Proendocrine genes coordinate the pancreatic islet differentiation program in vitro Genomewide expression analysis in zebrafish mind bomb alleles with pancreas defects of different severity identifies putative Notch responsive genes The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells.Protein therapy using MafA fused to a polyarginine transduction domain attenuates glucose levels of streptozotocin‑induced diabetic mice.Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis.MafA is a key regulator of glucose-stimulated insulin secretion.Predicting pancreas cell fate decisions and reprogramming with a hierarchical multi-attractor model.Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.Stem cells as a therapeutic target for diabetes.MafA is required for postnatal proliferation of pancreatic β-cells.FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice.Pancreatic stem/progenitor cells for the treatment of diabetes.Direct lineage conversions: unnatural but useful?Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans.Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.MAFA controls genes implicated in insulin biosynthesis and secretion Connectedness of PPI network neighborhoods identifies regulatory hub proteins.Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells Transcriptional factors, Mafs and their biological roles Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation.Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets.Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes.Glucose induces MafA expression in pancreatic beta cell lines via the hexosamine biosynthetic pathway.Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells.Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens.Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.

P2860

Q24309331-255CE892-F4D2-4024-A9AE-A13685A6718A Q24322398-5DA2BF36-DFEA-4300-ADAE-DCFF1D8A6F37 Q24626092-76631769-9A87-483A-BC60-7FA498D6CD65 Q24653598-662EE45F-5755-4A40-B0E3-840389674DEE Q24671057-7CB9616E-4DE1-4CAC-AD46-45316113B377 Q25256996-22CDCD2E-7878-4491-8BFA-58F701A4857B Q26827270-9B5AE8E1-6A37-4C4C-A39B-35BAFAE04291 Q28510639-80166C3C-70BA-4775-BD92-17D773E27932 Q28568114-3C807ACD-A4DD-44B2-AD94-053CF04A45F1 Q28579977-EEC21659-D559-416D-B411-7912615B64AB Q28588538-4B8D1FDB-EE72-4D9C-89CA-CC2B0EA8B345 Q28609723-F4100C40-E376-436C-9EE6-CACF59963200 Q28660898-11179AD7-3D77-4235-A098-CBE68D7C7558 Q30448603-952DB82D-05D5-45C2-96DB-BCE4BC4BE93A Q33316034-3ACFDC46-0070-434A-9843-DAFADBA69FC2 Q33320542-3FDD9806-339F-4A81-9132-AD4CB5AB57D4 Q33702044-3C75743B-0B92-4C57-A0B0-D9932D0758DC Q33733949-5FDA97C2-8A85-43BA-A010-BA52C8D8DA5B Q33836891-56C378B0-4B0C-415E-8297-2FE8AA336A4A Q33851580-B240A937-DA37-4BA4-B518-1E5C34CA8D69 Q33930262-C8E96165-CD6F-4BF6-8604-F130BDA1126A Q33982394-E5140213-0A03-4D60-91C0-FDA01D04F129 Q34050594-0957383D-1AA4-42E3-A6B3-1455495A2CC2 Q34116712-50F65051-54D1-456A-A946-5F86DA43D78A Q34148810-70A60F33-939F-4227-AC3B-BAE4AF00DAB6 Q34224069-9EF65F32-2821-45E4-A934-CB5DF68BE339 Q34338020-BF42611E-A355-4D56-9ED7-11024FABAB30 Q34412797-52B07431-676D-4964-9B8A-A424CF83C1D6 Q34450895-CE99C74E-C8DB-4B12-89E9-3F8D91C5F2E7 Q34588075-DE529741-B187-44D7-9DD4-36EB4E35A747 Q34771449-F4D556A5-34C0-4800-8517-03F399C3CDCE Q35028879-BF47211C-6730-4B50-8168-203101B8D050 Q35049862-76CE6B88-4650-4B32-A5AB-AE1F2A094C8A Q35585661-33D6D51D-26C8-495E-B90C-380CB5DA8F25 Q35714325-753FAB12-1333-45A9-A4DD-A8129450D753 Q35757146-8B615E8B-26EB-48EF-AB06-FF4F44C38ACB Q35865415-45DD72ED-F8BA-4FCB-816C-3AA7CEB9687B Q35880276-F02D49C8-24E5-40F2-BE3B-21BE3678850B Q35959737-8B0D1C04-0C21-4D9B-B9BE-9208DE22CB0E Q36067437-380BB8D6-97F9-496C-AA1A-2E493A1BB9B6

P2860

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

http://www.wikidata.org/entity/Q24531243

description

2002 nî lūn-bûn

@nan

2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Identification of beta-cell-sp ...... ctor RIPE3b1 as mammalian MafA

@nl

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@ast

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en-gb

type

label

Identification of beta-cell-sp ...... ctor RIPE3b1 as mammalian MafA

@nl

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@ast

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en-gb

prefLabel

Identification of beta-cell-sp ...... ctor RIPE3b1 as mammalian MafA

@nl

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@ast

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en-gb

P1433

Q24531243-71571FC4-88A4-4C52-85C6-AFF5F85FE812

P1476

Q24531243-D90951AB-4BA2-46DA-8647-FE58F5BBFCC9

P2093

Q24531243-2937D705-E728-41E3-BCF2-DA790353F1AC

Q24531243-5ED660A6-8E1D-4583-8916-27B1DDFCF781

Q24531243-C4007A67-0654-4F02-8AEB-D91554558F5A

Q24531243-E0EFD7C6-97ED-4A4A-8B95-5DC15868BB46

P2860

Q24531243-05B09222-D252-4C58-883F-72762C29B48D

Q24531243-05B42141-BE31-4A59-B218-B14207CD5CAE

Q24531243-08206192-46CB-46A4-B5C6-44D856CCDFA5

Q24531243-17545274-9F50-4957-BE17-4515194A9407

Q24531243-20C47838-8522-475D-88FB-A90290D89176

Q24531243-2619AD0F-73A8-4C93-BE35-A5761C3728AD

Q24531243-323F3382-5271-43A1-AD33-17D58C9DC536

Q24531243-428E66A2-F6CC-42DA-84BC-141D6733FFF7

Q24531243-4E2ED820-B029-4FCF-8095-F12CE06F7261

Q24531243-52944093-4EEE-4918-B1F3-55FC8FEBC91E

P304

Q24531243-ACB44381-5892-424A-8AE1-27A683D42B9A

P31

Q24531243-1E369840-8532-4D4D-BEAE-38CCF117253E

P356

Q24531243-B096B5B8-9F6D-45C4-AA38-21B2C7F29232

P407

Q24531243-7F83A80E-9FEA-4E11-8A8D-716FF75EC493

P433

Q24531243-C5596FB3-4CC6-4686-ADE5-AFC4F3BD3627

P478

Q24531243-70277326-B587-4CFA-A9BB-6AEE88924B91

P577

Q24531243-3D4479F5-B86A-46D3-AF9B-BF593627EC3B

P5875

Q24531243-32B774DF-9504-4FC7-9951-4DEF75285996

P698

Q24531243-A9D0A827-1779-4794-86B0-36934180FEDA

P921

Q24531243-D86207D3-B8E6-4159-81D3-3A84AF507499

P932

Q24531243-C471ADDA-BBEB-4E1A-A625-EAE88A7EA86F

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Identification of beta-cell-sp ...... tor RIPE3b1 as mammalian MafA.

@en

P2093

Arun Sharma

http://www.w3.org/2001/XMLSchema#string

Jonathan Rud

http://www.w3.org/2001/XMLSchema#string

Larry G Moss

http://www.w3.org/2001/XMLSchema#string

Martin Olbrot

http://www.w3.org/2001/XMLSchema#string

P2860

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation

Phosphorylation of MafA is essential for its transcriptional and biological properties

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

Rat maf-related factors: the specificities of DNA binding and heterodimer formation

Regulation of mouse lens fiber cell development and differentiation by the Maf gene

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

Insulin-promoter-factor 1 is required for pancreas development in mice

P304

6737-6742

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.102168499

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

99

http://www.w3.org/2001/XMLSchema#string

P577

2002-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11360930

http://www.w3.org/2001/XMLSchema#string

P698

12011435

http://www.w3.org/2001/XMLSchema#string

P921

P932

124472

http://www.w3.org/2001/XMLSchema#string