Signaling from Ras to Rac and beyond: not just a matter of GEFs.
about
A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathwaysKank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signalingCatalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinAffixin activates Rac1 via betaPIX in C2C12 myoblastAn effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machineHistone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosisActin binding proteins, spermatid transport and spermiationDiabetic complications in pregnancy: is resveratrol a solution?Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast.Evidence for direct interaction between Sprouty and CblHSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivoThe formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response elementSH2-Bbeta is a Rac-binding protein that regulates cell motilityTiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowthPhosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with DblMechanisms through which Sos-1 coordinates the activation of Ras and Rac.Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor.BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.Identification of a novel interaction of 14-3-3 with p190RhoGEF.Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activationThe Ras/Rac guanine nucleotide exchange factor mammalian Son-of-sevenless interacts with PACSIN 1/syndapin I, a regulator of endocytosis and the actin cytoskeleton.Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signalingProteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograft lesions: biomarkers of progression3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.Order and disorder: the role of extracellular matrix in epithelial cancer.Phagocytosis and macropinocytosis in Dictyostelium: phosphoinositide-based processes, biochemically distinct.Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.Characterization and functional analysis of the calmodulin-binding domain of Rac1 GTPaseNf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathwaysA computational framework for the topological analysis and targeted disruption of signal transduction networks.Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model.c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis.Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch.Salmonella enterica serovar Typhimurium requires nonsterol precursors of the cholesterol biosynthetic pathway for intracellular proliferationTargeting mutated tyrosine kinases in the therapy of myeloid leukaemias.Lipocalin-type prostaglandin D2 synthase protein regulates glial cell migration and morphology through myristoylated alanine-rich C-kinase substrate: prostaglandin D2-independent effectsTranscriptome analysis of HeLa cells response to Brucella melitensis infection: a molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis.
P2860
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P2860
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@ast
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@en
type
label
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@ast
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@en
prefLabel
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@ast
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@en
P2093
P2860
P356
P1433
P1476
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
@en
P2093
Di Fiore PP
Frittoli E
Giardina G
Innocenti M
Tocchetti A
P2860
P304
P356
10.1093/EMBOJ/19.11.2393
P407
P577
2000-06-01T00:00:00Z