Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
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LKB1 and AMPK differentially regulate pancreatic β-cell identity.Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects.S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength.Cdk5r1 Overexpression Induces Primary β-Cell Proliferation.High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation.SIKs control osteocyte responses to parathyroid hormoneThe prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion.Two Degradation Pathways of the p35 Cdk5 (Cyclin-dependent Kinase) Activation Subunit, Dependent and Independent of UbiquitinationPRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells.PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription.LKB1 couples glucose metabolism to insulin secretion in mice.LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemiapraja2 regulates KSR1 stability and mitogenic signalingThe clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.SIK2 regulates insulin secretion.
P2860
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P2860
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
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2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@ast
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@en
type
label
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@ast
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@en
prefLabel
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@ast
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@en
P2093
P2860
P921
P356
P1433
P1476
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
@en
P2093
Accalia Fu
Chantal Depatie
Courtney Reeks
Jun-Ichi Sakamaki
Mufida Al Azzabi
Nabeel Bardeesy
Robert A Screaton
Siu-Pok Yee
Stephen Baird
P2860
P2888
P304
P356
10.1038/NCB2919
P577
2014-03-01T00:00:00Z
P6179
1039539536