A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s.
about
Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysisThe E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysinesA unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeastRapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substratesA comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome systemProximity-induced activation of human Cdc34 through heterologous dimerization.Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteinsMMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathwayCue1p is an activator of Ubc7p E2 activity in vitro and in vivo.The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivoDimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chainsBuilding ubiquitin chains: E2 enzymes at workA novel family of ubiquitin-specific proteases in chick skeletal muscle with distinct N- and C-terminal extensions.The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination.The ubiquitin-proteasome pathway and synaptic plasticity.Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Creation of a pluripotent ubiquitin-conjugating enzyme.Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimerStructure-function analysis of yeast mRNA cap methyltransferase and high-copy suppression of conditional mutants by AdoMet synthase and the ubiquitin conjugating enzyme Cdc34p.Cdc34 self-association is facilitated by ubiquitin thiolester formation and is required for its catalytic activity.Getting into position: the catalytic mechanisms of protein ubiquitylation.Genome-Wide Identification, Phylogenetic and Expression Analyses of the Ubiquitin-Conjugating Enzyme Gene Family in MaizeSCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo.E2-EPF UCP Possesses E3 Ubiquitin Ligase Activity via Its Cysteine 118 Residue.Novel CDC34 (UBC3) ubiquitin-conjugating enzyme mutants obtained by charge-to-alanine scanning mutagenesis.Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzymeIntragenic suppression among CDC34 (UBC3) mutations defines a class of ubiquitin-conjugating catalytic domains.Identification of a positive regulator of the cell cycle ubiquitin-conjugating enzyme Cdc34 (Ubc3)Suramin inhibits cullin-RING E3 ubiquitin ligases.Multimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tailsThe acidic tail of the Cdc34 ubiquitin-conjugating enzyme functions in both binding to and catalysis with ubiquitin ligase SCFCdc4.The enzymes in ubiquitin-like post-translational modifications.Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression.Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34.Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzyme.Monte Carlo docking with ubiquitin.Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain.Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains.
P2860
Q22010136-1A6CBC1E-2E11-4624-89C5-B117BF1C7E09Q24294518-5821C616-C61A-4E9E-8A67-017D2CD1CD3EQ24303664-E6A88770-642D-4D6B-A903-BCFC7878D4B3Q24305063-5D9DFEF0-21D5-48D5-BC8F-972DD8A59CDFQ24320335-B11DE522-2EE3-49EA-9F0D-E9D667B194B7Q24322903-3D263677-02BD-4A7F-BF59-01511DFA8F8EQ24336529-F6770B9D-366B-445E-8BB1-14D900FCBFC9Q24530602-F25AE7B5-15EA-4E42-86CE-E20B2C8ACC10Q24802049-0404B417-29A6-481B-A1A4-911A61A0A57EQ27934604-985F3D16-7CF4-4C6A-8F1F-F7D48C810FECQ27938752-4C0DAC0E-4FE3-4F08-9149-9AFB68E29903Q27940309-ED146629-A8B9-41B0-82E7-CB625F188B4EQ28594243-F4260146-50C7-4879-AEF7-1F6437279526Q29619578-08CA29F6-1922-49D8-B9A9-49D33CCA9FD3Q32026630-72062EE2-59AF-4C30-8FDA-30EE87DDA8CDQ33885264-AEEA455D-584F-4D78-AA4B-36441A0F0069Q33994715-2BDBF6A6-7849-4321-AA71-233EFAA14D18Q34010063-D442038A-67CD-4C99-B2D1-7DB666D5DB85Q34012276-22479F74-7044-4967-BB07-0620125C3C5AQ34346819-BFE22979-8322-480C-ADCD-0D1A546A670EQ34610110-619237FA-9830-4745-8041-3B8FBE184BFFQ35161788-FA781FFC-E68A-4F79-877B-BBB822E173CAQ35681247-ACD4987A-9A49-42BC-BF2D-18A46B641FE8Q35852717-B4AE6987-B753-40DA-A727-36017C1139B5Q35950158-39871034-CED8-407D-BC6B-B505D12E16E3Q36148670-5A9028E7-68F0-4968-A1D9-B6E94CEAC003Q36549697-03F69C35-57FE-4271-9DF1-2996A491CEE6Q36554355-4EA8C65A-0AAE-4237-9074-21D9B450FF2CQ36555375-61C6DB2A-A589-4A03-93A9-93029E073C6FQ36557183-4D2F0273-3645-4CBF-9E90-1691784D4904Q36802367-392F0B7E-7523-4D73-A593-E80E302B9145Q37349016-FE377C40-89D0-450A-ACDA-89E6E51621CCQ37479215-73ACCF37-C015-45CB-8566-6CE51D51DA3BQ37681979-8436C2F7-E61D-4B43-8BEC-0ADCD167DF4FQ40140650-AF954913-EF58-42B0-9A70-19A641A8048AQ40337840-FB5EFB8D-A959-4D03-A2AC-8BE5450AA4ADQ41531902-198E515D-5159-4FF4-9F6A-AFA57C8AAFB7Q41828214-EF2C17B8-0D26-43AC-B047-C66DF0FCB0E6Q41879077-7148291E-2BD1-4BF8-B830-0DF25C997776Q42067617-900F6CF9-7D12-436E-8E47-6EF0206F61AA
P2860
A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s.
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
A chimeric ubiquitin conjugati ...... tion and evolution of the E2s.
@ast
A chimeric ubiquitin conjugati ...... tion and evolution of the E2s.
@en
type
label
A chimeric ubiquitin conjugati ...... tion and evolution of the E2s.
@ast
A chimeric ubiquitin conjugati ...... tion and evolution of the E2s.
@en
prefLabel
A chimeric ubiquitin conjugati ...... tion and evolution of the E2s.
@ast
A chimeric ubiquitin conjugati ...... tion and evolution of the E2s.
@en
P2093
P2860
P1433
P1476
A chimeric ubiquitin conjugati ...... ction and evolution of the E2s
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1992.TB05381.X
P407
P577
1992-08-01T00:00:00Z