Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. - Wikidata - wikimedia - TriplyDB

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

http://www.wikidata.org/entity/Q33943320

about

Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies The cell surface mucin podocalyxin regulates collective breast tumor budding.Sphingolipid regulation of ezrin, radixin, and moesin proteins family: implications for cell dynamics.Inactivation of Src-to-ezrin pathway: a possible mechanism in the ouabain-mediated inhibition of A549 cell migration Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box.Toward a drug development path that targets metastatic progression in osteosarcoma.ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion Eight proteins play critical roles in RCC with bone metastasis via mitochondrial dysfunction Bone Sarcomas in Pediatrics: Progress in Our Understanding of Tumor Biology and Implications for Therapy.The ezrin metastatic phenotype is associated with the initiation of protein translation.Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level.Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B-cell receptor signaling and tumor growth in diffuse large B-cell lymphoma.miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression.Discovery of biomarkers for osteosarcoma by proteomics approaches Directional memory arises from long-lived cytoskeletal asymmetries in polarized chemotactic cells.Caspase Cleavages of the Lymphocyte-oriented Kinase Prevent Ezrin, Radixin, and Moesin Phosphorylation during Apoptosis.Ezrin Inhibition Up-regulates Stress Response Gene Expression Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non-Small Cell Lung Cancer Cells.Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins Zebrafish Models of Prader-Willi Syndrome: Fast Track to Pharmacotherapeutics.The clinical significance of the Ezrin gene and circulating tumor cells in osteosarcoma.Ezrin expression and cell survival regulation in colorectal cancer The adolescent and young adult with cancer: state of the art -- bone tumors.Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology.Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-κB signaling that promotes colon cancer progression.Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal.15α-methoxypuupehenol Induces Antitumor Effects In Vitro and In Vivo against Human Glioblastoma and Breast Cancer Models.MicroRNA-144 inhibits the proliferation, apoptosis, invasion, and migration of osteosarcoma cell line F5M2.Establishment of Four New Human Primary Cell Cultures from Chemo-Naïve Italian Osteosarcoma Patients.Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma.CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity.Cutting Edge: Ezrin Regulates Inflammation by Limiting B Cell IL-10 Production.Ezrin is a Major Regulator of Membrane Tension in Epithelial Cells.The clinical significance of changes in ezrin expression in osteosarcoma of children and young adults.Involvement of intracellular transport in TREK-1c current run-up in 293T cells.Targeting Rho associated kinases in leukemia and myeloproliferative neoplasms.Sphingosine 1-phosphate activation of ERM contributes to vascular calcification.Current Tissue Molecular Markers in Colorectal Cancer: A Literature Review.Ezrin mediates both HGF/Met autocrine and non-autocrine signaling-induced metastasis in melanoma.Osteosarcoma: Accelerating Progress Makes for a Hopeful Future.

P2860

Q26782646-620DCAB8-D33C-43AB-85D8-1B48062EF70E Q27338644-ABE8A1A5-150B-4A2C-A443-AC9784DBAF0A Q27691440-F5C0A083-1796-4409-B082-37A9A0573CCE Q28391063-E45D4C8B-69EC-4515-A39C-DDBD148AF90B Q30488315-3206DA7B-FC22-4709-8957-F0FA0A7C2EA4 Q34052760-3FEEAB2E-1785-4B5A-B357-C302D55DBE25 Q35005380-53EE46FB-0D8F-481D-ABEE-519D6C8CBEAF Q35675971-6ED08D87-0BE6-449F-8BA7-809C7A332462 Q35894540-98F06F70-88C7-44EC-8D44-C0F759C2814F Q35949767-B385ABAE-2FA7-4942-B4E6-E4C556E6D244 Q35963798-00C828B9-7046-47A3-BC0D-FCB7F53EBE1D Q36021623-C30F0D66-0778-47EE-8F51-34B8679C2372 Q36107781-6728483F-3BA3-4859-9727-BAD63DB21FE7 Q36440338-8B9E610D-2F66-4AD1-88E0-41A25271F940 Q36563420-1FAB03B6-2912-4D7E-A95F-9D1221CC7A89 Q36876186-6F656FB7-2317-4613-9F63-F02C59C6862C Q37065917-42DAFA92-4DFF-43F1-AC2E-A071471DC8E6 Q37218007-DDAA37EA-4BD1-4A0E-A70A-6693A1C56246 Q37295377-D38B4BCD-4710-4CE6-B62D-F2CF365BB284 Q37415613-AF078D27-E26F-4FFC-9517-EF9BC53DECCC Q37641447-92A6F318-FBE3-47A9-996D-49FE9AAF4BFC Q37682332-DCA83502-B227-4EBD-BEC3-A10E801214E0 Q38108248-40712566-CE88-430E-8796-F2FC2375419C Q38220804-8CCFC861-3244-4337-9D87-87E1F511D25A Q38322908-B3994EF3-61C6-4104-B190-3582D7829DA5 Q38349935-C606CAE7-9EA6-47B0-AD13-8CC6AC0E866A Q38722193-4DACC102-96E7-490D-AD0D-CE283671D9EF Q38889691-CF8DF993-FB11-4162-8373-DD37709F6E7B Q38895148-F4BCFE00-23BB-46BF-95F4-82E62BB5D7F1 Q39044688-D298E584-AFA6-4FBC-B439-B2F98966470D Q39156193-4A212C7E-A477-4D3C-BD28-8422A33C6CA8 Q40206439-77C8956B-5738-433F-ACE6-402A1F5880E0 Q40468734-7836CBF3-377D-4F35-B3C0-79FD86EA66B1 Q40516293-42C0C56A-2CB9-41CD-A0D7-59541C14B4DE Q42032276-AB1DBFF5-D9E7-45A6-8272-D3E7F73F7C02 Q43155856-8749B7A9-9849-4CDF-A740-129B0FC44F5E Q46273824-2D06F2FD-231B-4AD2-8841-D1334622CB0D Q47094355-66551023-3AB5-4B46-AC03-1DFC07B2996F Q47360764-2FEDFDDB-B343-4686-8138-1B443BD7DD4B Q49484270-A6F83E57-5A9E-4C52-8865-F0935CBC1D90

P2860

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

http://www.wikidata.org/entity/Q33943320

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

@ast

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

@en

type

label

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

@ast

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

@en

prefLabel

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

@ast

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

@en

P1433

Q33943320-5ECB8039-769E-4550-AD38-3ACE7125E4DA

P1476

Q33943320-9345EA7A-4B87-4434-B18B-ADDF25D3617A

P2093

Q33943320-0309557A-4EBC-4491-89DC-425BD865C3DF

Q33943320-11A67D7B-64B6-4F99-A23F-4D16EC03F951

Q33943320-2823A81F-DF82-4DF8-9504-D75B2BEEFEC7

Q33943320-378E2DA8-B70B-4BA9-95C0-8B6451E94BAD

Q33943320-4387A8ED-15ED-43F5-A4B3-EE3E35CE9144

Q33943320-8AE4CDA4-F062-4B1D-9A02-0C296BE22E6E

Q33943320-B18171B8-AF37-48CB-B33B-AE145066C5F7

Q33943320-D0D74525-0DA8-4BB1-BC33-850B26514ABA

Q33943320-D28E7EF3-3996-485B-BAD6-C8978EB6FAFA

Q33943320-DF44FA38-65CE-4C7D-A4B6-EC806B768B94

P2860

Q33943320-039E7EE4-1A7F-4EE7-BF4B-C4454D6C78FB

Q33943320-0CBB0EA3-F0BB-4C9E-880B-D2E37680FCDD

Q33943320-0D979E0A-3CE5-42FF-90F5-B5458DDF04C5

Q33943320-122DA36F-3B57-4BF5-9CB7-C9A31289672E

Q33943320-16F724BD-9E5C-437F-B726-227DD2DCEE97

Q33943320-18DFE2FA-3148-4505-AC19-C62BDFF263AE

Q33943320-252251BE-EEEB-4538-B59E-A795EB8F0C9A

Q33943320-2BD74237-B1BC-4418-97D0-CE9E521B7A47

Q33943320-2E5AC5D6-C7A7-4F3E-8CB5-DFD671DC6C1B

Q33943320-383FDBEC-3E3C-4528-B9BB-A8A1C04F6B80

P2888

Q33943320-6F5C470D-026A-4ACA-A11D-662123DC473A

P304

Q33943320-7AD295D0-0796-428A-BCA4-C146F2026B00

P31

Q33943320-AFAC5D76-FF8B-41D5-AE48-CF2EFCECB533

P356

Q33943320-592E598C-AFBE-4116-B10C-18F89E413B6D

P407

Q33943320-41ED0823-F8FC-4738-B125-F06D1049DA5D

P433

Q33943320-85EF7172-390B-4936-AE5B-D15887D6565C

P478

Q33943320-45FBDFA4-38E4-4C5C-85C5-A56BA332684B

P50

Q33943320-60E26084-6381-40B1-BDEB-BC964493D05E

Q33943320-87DBF691-B8C5-4240-939E-FA94AE88C74B

P577

Q33943320-3A696673-DFC9-44BA-9BCB-5B632486EF91

P5875

Q33943320-A39BF43C-CEA6-419B-BB06-5D667F2FABB1

P6179

Q33943320-646712E9-896D-4983-B8D8-6CEC7AC2D66A

P698

Q33943320-A1999C9B-4A49-44CF-B14A-C81578358624

P932

Q33943320-D841A9FA-D6FF-47BB-9C01-D95B57AE8D1C

P356

P1433

P1476

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells

@en

P2093

A Uren

http://www.w3.org/2001/XMLSchema#string

C Khanna

http://www.w3.org/2001/XMLSchema#string

E M Beauchamp

http://www.w3.org/2001/XMLSchema#string

G Bulut

http://www.w3.org/2001/XMLSchema#string

G W Kosturko

http://www.w3.org/2001/XMLSchema#string

H-S Lee

http://www.w3.org/2001/XMLSchema#string

J A Toretsky

http://www.w3.org/2001/XMLSchema#string

K Chen

http://www.w3.org/2001/XMLSchema#string

S Dakshanamurthy

http://www.w3.org/2001/XMLSchema#string

S Rahim

http://www.w3.org/2001/XMLSchema#string

P2860

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane

The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells

Stages of embryonic development of the zebrafish

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Organizing the cell cortex: the role of ERM proteins

P2888

P304

269-281

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/ONC.2011.245

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-06-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51250629

http://www.w3.org/2001/XMLSchema#string

P6179

1048437792

http://www.w3.org/2001/XMLSchema#string

P698

21706056

http://www.w3.org/2001/XMLSchema#string

P932

3513970

http://www.w3.org/2001/XMLSchema#string