Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression.
about
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTENFez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.PTEN function: how normal cells control it and tumour cells lose itCritical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformationNo evidence for involvement of SDHD in neuroblastoma pathogenesisPten dose dictates cancer progression in the prostatePhosphoinositides: tiny lipids with giant impact on cell regulationGenetically engineered mouse models of prostate cancerFISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome.HCV infection-associated hepatocellular carcinoma in humanized miceRegulation of PTEN stability and activity by Plk3Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in ChordomaPooled analysis of loss of heterozygosity in breast cancer: a genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions.Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of PtenMolecular genetics of human prostate cancer.Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(+/-) mouseDeregulation of FoxO3a accelerates prostate cancer progression in TRAMP miceAndrogen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivo.Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process.Loss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasia3'UTR shortening identifies high-risk cancers with targeted dysregulation of the ceRNA network.The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostatesCooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.Role of SV40 integration site at chromosomal interval 1q21.1 in immortalized CRL2504 cells.Prostate cancer-specific and potent antitumor effect of a DD3-controlled oncolytic virus harboring the PTEN gene.The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.Impaired Pten expression in human malignant peripheral nerve sheath tumours.Reduction of Pten dose leads to neoplastic development in multiple organs of Pten (shRNA) miceProstate adenocarcinoma: cellular and molecular abnormalities.Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma.A Drosophila model of multiple endocrine neoplasia type 2.p18 Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control.Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifierFISH analysis of PTEN in endometrial carcinoma. Comparison with SNP arrays and MLPA.Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas.PTEN: Multiple Functions in Human Malignant TumorsHuman cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability
P2860
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P2860
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@ast
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@en
type
label
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@ast
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@en
prefLabel
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@ast
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@en
P2093
P2860
P356
P1476
Haploinsufficiency of the Pten ...... s prostate cancer progression.
@en
P2093
B Kwabi-Addo
K Podsypanina
N Greenberg
P2860
P304
11563-11568
P356
10.1073/PNAS.201167798
P407
P577
2001-09-11T00:00:00Z