A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin
about
Steroidogenesis in the skin: implications for local immune functionsNew vitamin D analogs as potential therapeutics in melanomaVitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytesVitamin D2-enriched button mushroom (Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic miceSequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skinPsychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.11β-hydroxysteroid dehydrogenase 1 specific inhibitor increased dermal collagen content and promotes fibroblast proliferation.20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes.Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity.Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity.Vitamin D supplementation during pregnancy: safety considerations in the design and interpretation of clinical trials.Vitamin d and its relationship with obesity and muscle.Extra-adrenal glucocorticoids and mineralocorticoids: evidence for local synthesis, regulation, and function.Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system.Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomesKey role of CRF in the skin stress response system.A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiologyActivity of 25-hydroxylase in human gingival fibroblasts and periodontal ligament cells.Current concepts of metastasis in melanoma.Lumisterol is metabolized by CYP11A1: discovery of a new pathwayNeuroendocrinology of the skin: An overview and selective analysisCultured human dermal fibroblasts do produce cortisol.Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides.20-Hydroxyvitamin D3, a product of vitamin D3 hydroxylation by cytochrome P450scc, stimulates keratinocyte differentiationPathways and products for the metabolism of vitamin D3 by cytochrome P450sccTranscriptome analysis of skin photoaging in chinese females reveals the involvement of skin homeostasis and metabolic changes.20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.Vitamin D analogs 17,20S(OH)2pD and 17,20R(OH)2pD are noncalcemic and exhibit antifibrotic activity.Immunomodulatory effects of sex hormones: requirements for pregnancy and relevance in melanoma.Vitamin D and skin cancer.Macrophage migration inhibitory factor: a central regulator of wound healing.Chronic stress suppresses the expression of cutaneous hypothalamic-pituitary-adrenocortical axis elements and melanogenesis.Production of 22-hydroxy metabolites of vitamin d3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cellsCutaneous hypothalamic-pituitary-adrenal axis homolog: regulation by ultraviolet radiationMetabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1Corticotropin releasing hormone and the skin.Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture.Stress-linked cortisol concentrations in hair: what we know and what we need to know.
P2860
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P2860
A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A novel pathway for sequential ...... 50scc system in mammalian skin
@ast
A novel pathway for sequential ...... 50scc system in mammalian skin
@en
type
label
A novel pathway for sequential ...... 50scc system in mammalian skin
@ast
A novel pathway for sequential ...... 50scc system in mammalian skin
@en
prefLabel
A novel pathway for sequential ...... 50scc system in mammalian skin
@ast
A novel pathway for sequential ...... 50scc system in mammalian skin
@en
P2093
P2860
P50
P1433
P1476
A novel pathway for sequential ...... 50scc system in mammalian skin
@en
P2093
Alexander Pisarchik
Chuck Dunbar
Jacobo Wortsman
Jeremy Stewart
Robert C Tuckey
Trevor Sweatman
P2860
P304
P356
10.1111/J.1432-1033.2004.04356.X
P407
P577
2004-11-01T00:00:00Z