Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.
about
Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNASearching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA GlycosylaseDNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeHuman base excision repair creates a bias toward -1 frameshift mutationsRecent advances in the structural mechanisms of DNA glycosylasesMammalian base excision repair: the forgotten archangelMolecular pathways undergoing dramatic transcriptomic changes during tumor development in the human colon.Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase.Enzymatic MPG DNA repair assays for two different oxidative DNA lesions reveal associations with increased lung cancer riskNaturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease.Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae.N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents.Mechanisms of glycosylase induced genomic instabilityN-methylpurine DNA glycosylase and OGG1 DNA repair activities: opposite associations with lung cancer risk.Balancing repair and tolerance of DNA damage caused by alkylating agentsContributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents.A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD.A TetR family transcriptional factor directly regulates the expression of a 3-methyladenine DNA glycosylase and physically interacts with the enzyme to stimulate its base excision activity in Mycobacterium bovis BCGMultifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities.N-methylpurine DNA glycosylase plays a pivotal role in the threshold response of ethyl methanesulfonate-induced chromosome damage.Detected microsatellite polymorphisms in genetically altered inbred mouse strains.
P2860
Q26864622-BB505643-1AC3-48E5-BEEB-7E6B7C66C94FQ27667051-C5AD4CD4-33BB-4F1C-B5C3-42E7BEE3F107Q27676011-C6511D22-2DD0-43D1-A24C-481561114AEAQ28709604-8E4CF41C-4B1C-43DD-A46B-C0035FB4F70FQ34055705-C532C3E7-11B3-45D6-B191-B5B9A41F5F42Q34306735-EC737642-BA30-4A05-A9D2-AFAFFE5B8B9EQ34327812-BFA788AB-32E5-4368-9B49-DBBE4F8AD30EQ34518059-CC0A8E40-F239-4BFD-A71C-7DA09A6FB15AQ34687289-27A2B478-D522-4456-B75E-4B2F2629EF39Q35003614-C0353118-4542-44C5-BDE3-0ABA7B8EA5A4Q35118112-96E48B0F-B5AD-4764-8934-0D7D3D2AB722Q35748265-6E5182EA-2D98-4408-997B-26A4E7DD03BDQ36137812-ECC3EC43-235D-4220-81EE-B317B4984819Q36319705-C2157FE4-9C8A-47B5-8272-F34225A18CD6Q36411751-40209D04-20E9-4146-8D29-37D9A290D0A5Q36651488-89578898-2233-4377-AF70-9192369EEA5DQ36759955-E2DBD6CD-CB7A-4FB8-A2B2-63B5EAEFE2F6Q37279194-57A900D9-8347-4E8C-8596-6E5F17900534Q37691642-C172504F-CE20-4AF6-A862-104223116E25Q37861732-52E7DAF1-4C18-4FA7-BA29-D2961D98C14AQ38019607-4EAC79C4-A35C-4ADB-8B47-687BBCA981FAQ38999756-8F4DAFA6-9C32-4B9B-80BA-89423B97CF3FQ39632856-572A171F-02D7-46EB-888E-60890ADA4A63Q44092552-3F7EDBA2-B125-45D3-85EA-273CBCDDB156
P2860
Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Frameshift mutagenesis and mic ...... alkyladenine DNA glycosylase.
@ast
Frameshift mutagenesis and mic ...... alkyladenine DNA glycosylase.
@en
type
label
Frameshift mutagenesis and mic ...... alkyladenine DNA glycosylase.
@ast
Frameshift mutagenesis and mic ...... alkyladenine DNA glycosylase.
@en
prefLabel
Frameshift mutagenesis and mic ...... alkyladenine DNA glycosylase.
@ast
Frameshift mutagenesis and mic ...... alkyladenine DNA glycosylase.
@en
P2093
P2860
P1433
P1476
Frameshift mutagenesis and mic ...... n alkyladenine DNA glycosylase
@en
P2093
Ayelet Moar-Shoshani
Dharini Shah
Gondichatnahalli M Lingaraju
Joanna Klapacz
Lawrence A Loeb
Leona D Samson
P2860
P304
P356
10.1016/J.MOLCEL.2010.01.038
P577
2010-03-01T00:00:00Z