Somatic NF1 mutational spectrum in benign neurofibromas: mRNA splice defects are common among point mutations.

Somatic NF1 mutational spectrum in benign neurofibromas: mRNA splice defects are common among point mutations.

Item
http://www.wikidata.org/entity/Q33951727
Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and RasDissecting loss of heterozygosity (LOH) in neurofibromatosis type 1-associated neurofibromas: Importance of copy neutral LOH.Genetics of neurofibromatosis 1-associated peripheral nerve sheath tumors.PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formationNf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.Mosaic RASopathies.Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancerAlternative splicing and disease.Biomarkers for malignant peripheral nerve sheath tumours.A mild neurofibromatosis type 1 phenotype produced by the combination of the benign nature of a leaky NF1-splice mutation and the presence of a complex mosaicism
P2860

Somatic NF1 mutational spectrum in benign neurofibromas: mRNA splice defects are common among point mutations.

Item
http://www.wikidata.org/entity/Q33951727
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Somatic NF1 mutational spectru ...... common among point mutations.
@ast
Somatic NF1 mutational spectru ...... common among point mutations.
@en
type
label
Somatic NF1 mutational spectru ...... common among point mutations.
@ast
Somatic NF1 mutational spectru ...... common among point mutations.
@en
prefLabel
Somatic NF1 mutational spectru ...... common among point mutations.
@ast
Somatic NF1 mutational spectru ...... common among point mutations.
@en
P1433
P1476
P2093
P2888
P304
P31
P356
P433
P478
P50
P577
P6179
P698
P356
P1433
P1476
Somatic NF1 mutational spectru ...... common among point mutations.
@en
P2093
P2888
P304
P31
P356
P433
P478
P50
P577
P6179
P698