Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels
about
Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 α subunitsSymplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca spBloom Dynamics of Cyanobacteria and Their Toxins: Environmental Health Impacts and Mitigation StrategiesMarine cyanobacteria compounds with anticancer properties: a review on the implication of apoptosisBrevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cellsDiversity and impact of prokaryotic toxins on aquatic environments: a reviewQ28828244Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockersA fast Na+/Ca2+-based action potential in a marine diatom.Ichthyotoxic brominated diphenyl ethers from a mixed assemblage of a red alga and cyanobacterium: structure clarification and biological properties.Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channelsChemical construction and structural permutation of neurotoxic natural product, antillatoxin: importance of the three-dimensional structure of the bulky side chain.Biologically active secondary metabolites from marine cyanobacteriaThe twisted side chain of antillatoxin is important for potent toxicity: total synthesis and biological evaluation of antillatoxin and analogues.Biological targets and mechanisms of action of natural products from marine cyanobacteria.Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neuronsBioactive compounds from cyanobacteria and microalgae: an overview.Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, AntillatoxinPharmacology and toxicology of pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida EvergladesShellfish toxins targeting voltage-gated sodium channels.Recent progress in neuroactive marine natural products.Marine natural product drug discovery: Leads for treatment of inflammation, cancer, infections, and neurological disorders.Total synthesis and functional analysis of non-ribosomal peptides.A review of pharmacological and toxicological potentials of marine cyanobacterial metabolites.Advances in targeting voltage-gated sodium channels with small molecules.The bulky side chain of antillatoxin is important for potent toxicity: rational design of photoresponsive cytotoxins based on SAR studies.Activation of sodium channels by α-scorpion toxin, BmK NT1, produced neurotoxicity in cerebellar granule cells: an association with intracellular Ca2+ overloading.Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons.Prediction of biological activity profiles of cyanobacterial secondary metabolites.Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria.Marine Toxins That Target Voltage-gated Sodium Channels.Mechanisms and Effects Posed by Neurotoxic Products of Cyanobacteria/Microbial Eukaryotes/Dinoflagellates in Algae Blooms: a Review.
P2860
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P2860
Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@ast
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@en
type
label
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@ast
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@en
prefLabel
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@ast
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@en
P2093
P2860
P356
P1476
Antillatoxin is a marine cyano ...... voltage-gated sodium channels
@en
P2093
F W Berman
F Yokokawa
T F Murray
W H Gerwick
P2860
P304
P356
10.1073/PNAS.121085898
P407
P577
2001-06-01T00:00:00Z