Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element.
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Rabbit as a novel animal model for hepatitis E virus infection and vaccine evaluationThe open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaquesHepatitis E Virus Mutations: Functional and Clinical RelevanceMolecular Biology and Infection of Hepatitis E VirusReview article: hepatitis E-a concise review of virology, epidemiology, clinical presentation and therapy.Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.Experimental infection of rabbits with rabbit and genotypes 1 and 4 hepatitis E virusesCapped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.Systematic pathogenesis and replication of avian hepatitis E virus in specific-pathogen-free adult chickens.Open reading frame 3 of genotype 1 hepatitis E virus inhibits nuclear factor-κappa B signaling induced by tumor necrosis factor-α in human A549 lung epithelial cellsHepatitis E virus ORF2 protein activates the pro-apoptotic gene CHOP and anti-apoptotic heat shock proteinsEnhancement of interferon induction by ORF3 product of hepatitis E virus.Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on open reading frame 3 protein and requires an intact PXXP motif.Molecular virology of hepatitis E virus.Hepatitis E virus inhibits type I interferon induction by ORF1 productsConstruction of an infectious cDNA clone of avian hepatitis E virus (avian HEV) recovered from a clinically healthy chicken in the United States and characterization of its pathogenicity in specific-pathogen-free chickens.The nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus genome are critical for virus replication.Molecular biology and replication of hepatitis E virus.Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant.Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs.Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.Mutational analysis of the hypervariable region of hepatitis e virus reveals its involvement in the efficiency of viral RNA replicationNew Methods in Tissue Engineering: Improved Models for Viral InfectionDetection of negative-sense RNA in packaged hepatitis E virions by use of an improved strand-specific reverse transcription-PCR methodAdaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination.Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs.The hepatitis E virus capsid C-terminal region is essential for the viral life cycle: implication for viral genome encapsidation and particle stabilizationDeletions of the hypervariable region (HVR) in open reading frame 1 of hepatitis E virus do not abolish virus infectivity: evidence for attenuation of HVR deletion mutants in vivo.The hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics.Hepatitis E vaccine.A rat model for hepatitis E virus.In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent proteinHepatitis E virus genotype 1 infection of swine kidney cells in vitro is inhibited at multiple levelsHepatitis e: molecular virology and pathogenesis.In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and repliconsThe hepatitis E virus nonstructural polyprotein.Establishment of hepatitis E virus infection-permissive and -non-permissive human hepatoma PLC/PRF/5 subclones.Animal Models for Hepatitis E Virus.HEV Cell Culture.
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P2860
Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@ast
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@en
type
label
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@ast
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@en
prefLabel
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@ast
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@en
P2093
P2860
P356
P1476
Recombinant hepatitis E virus ...... ery of a cis-reactive element.
@en
P2093
M St Claire
R H Purcell
S Govindarajan
S U Emerson
P2860
P304
15270-15275
P356
10.1073/PNAS.251555098
P407
P577
2001-12-11T00:00:00Z