Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression - Wikidata - wikimedia - TriplyDB

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression

http://www.wikidata.org/entity/Q33956097

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From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity Targeting LKB1 in cancer - exposing and exploiting vulnerabilities Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints Genomic landscape of human papillomavirus-associated cancers Update in Lung Cancer 2014 CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.Genomic profiling toward precision medicine in non-small cell lung cancer: getting beyond EGFR The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma.Expression of programmed death-1 ligand (PD-L1) in tumor-infiltrating lymphocytes is associated with favorable spinal chordoma prognosis.The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.Lkb1 maintains Treg cell lineage identity.Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors.Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy.Genomic analysis of metastatic cutaneous squamous cell carcinoma.Is 5´-AMP-Activated Protein Kinase Both Jekyll and Hyde in Bladder Cancer?Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma.PD-L1 expression associated with better response to EGFR tyrosine kinase inhibitors SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.Why has active immunotherapy not worked in lung cancer?LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases.LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response.The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution.Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas.EML4-ALK enhances programmed cell death-ligand 1 expression in pulmonary adenocarcinoma via hypoxia-inducible factor (HIF)-1α and STAT3 miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint Squamous Cell Cancers: A Unified Perspective on Biology and Genetics SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer.PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer.Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.MiR-93 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer Cells by Activating the PI3K/Akt Pathway via Inhibition of LKB1/PTEN/CDKN1A.Non-small-cell lung cancers: a heterogeneous set of diseases.The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome The double-edged sword of AMPK signaling in cancer and its therapeutic implications.

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P2860

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression

http://www.wikidata.org/entity/Q33956097

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Loss of Lkb1 and Pten leads to ...... with elevated PD-L1 expression

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Loss of Lkb1 and Pten leads to ...... with elevated PD-L1 expression

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J.CCR.2014.03.033

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Abigail Altabef

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Adam J Bass

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Anil K Rustgi

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Carla F Kim

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Christine M Fillmore

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Chunxiao Xu

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Diego H Castrillon

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Glenn Dranoff

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Gordon J Freeman

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Grit S Herter-Sprie

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P2860

Evidence that SOX2 overexpression is oncogenic in the lung

Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Characterizing the cancer genome in lung adenocarcinoma.

Cancer statistics, 2013

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

Comprehensive genomic characterization of squamous cell lung cancers.

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10.1016/J.CCR.2014.03.033

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