The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
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Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosisA balancing act: efflux/influx in mycobacterial drug resistanceThe crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug designThe mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kineticsAccess channel residues Ser315 and Asp137 in Mycobacterium tuberculosis catalase-peroxidase (KatG) control peroxidatic activation of the pro-drug isoniazidUse of multiplex allele-specific polymerase chain reaction (MAS-PCR) to detect multidrug-resistant tuberculosis in PanamaIdentification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosisMultidrug resistant Mycobacterium tuberculosis: a retrospective katG and rpoB mutation profile analysis in isolates from a reference center in BrazilA riboswitch-based inducible gene expression system for mycobacteriaMechanisms of action of isoniazidTargeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitorsTranscriptional analysis of Mycobacterium fortuitum cultures upon hydrogen peroxide treatment using the novel standard rrnA-P1.Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, ChinaRapid detection of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis by high-resolution melting analysisIsoniazid-resistance conferring mutations in Mycobacterium tuberculosis KatG: catalase, peroxidase, and INH-NADH adduct formation activitiesUptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis.Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigs.Detection of isoniazid-resistant Mycobacterium tuberculosis strains by a multiplex allele-specific PCR assay targeting katG codon 315 variationUse of the genotype MTBDR assay for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis complex isolates.High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996 to 2001.The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions.In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions.N'-[(3-Methyl-2-thien-yl)carbon-yl]isonicotinohydrazide(E)-N'-(3-Benz-yloxy-4-methoxy-benzyl-idene)isonicotinohydrazideN'-(Cyclo-hexyl-carbon-yl)isonicotino-hydrazide(E)-N'-(2,4,5-Trimethoxy-benzyl-idene)isonicotinohydrazide dihydrate.(E)-N'-(2,4,6-Trihydroxy-benzyl-idene)isonicotinohydrazide sesquihydrate.(E)-N'-(2,3,4-Trimethoxy-benzyl-idene)isonicotinohydrazide(E)-N'-(2-Benzyl-oxybenzyl-idene)isonicotinohydrazide methanol solvate monohydrate.(E)-N'-[(E)-2-Methyl-pent-2-enyl-idene]isonicotinohydrazide.(E)-N'-(2,4,6-Trimethyl-benzyl-idene)isonicotinohydrazide.(E)-N'-(2,4,5-Trifluorobenzyl-idene)isonicotinohydrazide monohydrate.Bis{(E)-N'-[2,4-bis(trifluoro-meth-yl)benzyl-idene]isonicotinohydrazide} monohydrate.(E)-N'-(2,3,4-Trihy-droxy-benzyl-idene)-isonicotinohydrazide dihydrate.The pharmacogenetics of NAT: structural aspects.Current status and future development of antitubercular chemotherapy.Molecular characterization of rifampin- and isoniazid-resistant Mycobacterium tuberculosis strains isolated in PolandTuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy.Evaluation of molecular-Beacon, TaqMan, and fluorescence resonance energy transfer probes for detection of antibiotic resistance-conferring single nucleotide polymorphisms in mixed Mycobacterium tuberculosis DNA extracts.Inhibition of Mycobacterium tuberculosis AhpD, an element of the peroxiredoxin defense against oxidative stress.
P2860
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P2860
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
@ast
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
@en
type
label
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
@ast
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
@en
prefLabel
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
@ast
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
@en
P1476
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis
@en
P2093
P304
P356
10.1016/S1286-4579(00)00359-2
P577
2000-05-01T00:00:00Z