Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor.
about
Susceptibility of the aging lung to environmental injuryOverexpression of MYC causes p53-dependent G2 arrest of normal fibroblastsRegulation and localization of the Bloom syndrome protein in response to DNA damageTBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescenceCARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathwayPTEN regulation by Akt-EGR1-ARF-PTEN axisAlternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback controlControl of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1p19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland developmentmiR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progressionUpregulation of the let-7 microRNA with precocious development in lin-12/Notch hypermorphic Caenorhabditis elegans mutantsp38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanismsMel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteinsDevelopmental context determines latency of MYC-induced tumorigenesisRedox regulation of FoxO transcription factorsDSS1 is required for the stability of BRCA2Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathwayShort Telomeres in Key Tissues Initiate Local and Systemic Aging in ZebrafishThe proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescenceARF functions as a melanoma tumor suppressor by inducing p53-independent senescenceOxygen sensitivity severely limits the replicative lifespan of murine fibroblastsA functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.Quantification of epithelial cells in coculture with fibroblasts by fluorescence image analysis.Quantitative model of cell cycle arrest and cellular senescence in primary human fibroblasts.Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line.Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma.MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts.BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer.The inflammatory network: bridging senescent stroma and epithelial tumorigenesis.p35 is required for CDK5 activation in cellular senescence.The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines.Ectopic expression of E2F1 stimulates beta-cell proliferation and function.Human ARF protein interacts with topoisomerase I and stimulates its activity.Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblastsDeletion analysis of BMI1 oncoprotein identifies its negative regulatory domainRole of p14(ARF) in replicative and induced senescence of human fibroblasts.
P2860
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P2860
Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor.
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@ast
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@en
type
label
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@ast
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@en
prefLabel
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@ast
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@en
P2093
P2860
P1476
Regulation of a senescence che ...... and p14(ARF) tumor suppressor.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.1.273-285.2000
P407
P577
2000-01-01T00:00:00Z