mTOR Signaling from Cellular Senescence to Organismal Aging
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Changes in Regenerative Capacity through LifespanMilk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent TranslationThe pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitusRedox control of senescence and age-related diseaseDeletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptationPersistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing.Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilizationOrally administrated Lactobacillus pentosus var. plantarum C29 ameliorates age-dependent colitis by inhibiting the nuclear factor-kappa B signaling pathway via the regulation of lipopolysaccharide production by gut microbiota.The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca²⁺-release channel.DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblastsDoxorubicin and cyclophosphamide induce cognitive dysfunction and activate the ERK and AKT signaling pathwaysRAC3 more than a nuclear receptor coactivator: a key inhibitor of senescence that is downregulated in aging.Rapamycin reverses the senescent phenotype and improves immunoregulation of mesenchymal stem cells from MRL/lpr mice and systemic lupus erythematosus patients through inhibition of the mTOR signaling pathway.A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction.Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging.Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing.Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity.Virus/Host Cell Crosstalk in Hypoxic HPV-Positive Cancer Cells.Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR.Aging: Molecular Pathways and Implications on the Cardiovascular System.Disruption of dopamine homeostasis has sexually dimorphic effects on senescence characteristics of Drosophila melanogaster.mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome.
P2860
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P2860
mTOR Signaling from Cellular Senescence to Organismal Aging
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
mTOR Signaling from Cellular Senescence to Organismal Aging
@ast
mTOR Signaling from Cellular Senescence to Organismal Aging
@en
type
label
mTOR Signaling from Cellular Senescence to Organismal Aging
@ast
mTOR Signaling from Cellular Senescence to Organismal Aging
@en
prefLabel
mTOR Signaling from Cellular Senescence to Organismal Aging
@ast
mTOR Signaling from Cellular Senescence to Organismal Aging
@en
P2093
P2860
P356
P1433
P1476
mTOR Signaling from Cellular Senescence to Organismal Aging
@en
P2093
P2860
P304
P356
10.14336/AD.2014.0500263
P577
2013-12-05T00:00:00Z