Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.
about
Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysisHMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme AThe vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein BaxA quarter century of granzymesBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisPlasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysisThe histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen speciesCytotoxic T cells in AIDS colonic cryptosporidiosisCell death and autophagy in tuberculosisCharacterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compoundGranzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid.Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis.Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis.Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario.Granzyme A activates another way to dieCytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.Natural killer cells eradicate galectin-1-deficient glioma in the absence of adaptive immunity.Unique and overlapping substrate specificities of caspase-8 and caspase-10.The triterpenoid pristimerin induces U87 glioma cell apoptosis through reactive oxygen species-mediated mitochondrial dysfunctionPerforin-mediated target-cell death and immune homeostasis.Death by a thousand cuts: granzyme pathways of programmed cell deathDeerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax.The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.Expression of Bcl-2 family member Bid in normal and malignant tissues.Granzymes and perforin in solid organ transplant rejection.Granzyme B: a natural born killer.Nonredundant role of Bax and Bak in Bid-mediated apoptosis.Regulation of apoptosis by Bcl-2 family proteins.A protein encoded by the bovine herpesvirus 1 latency-related gene interacts with specific cellular regulatory proteins, including CCAAT enhancer binding protein alpha.TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability.The protein structures that shape caspase activity, specificity, activation and inhibition.Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C releasePerforin and lymphohistiocytic proliferative disorders.Human and murine granzyme B exhibit divergent substrate preferencesImpaired apoptosis and immune senescence - cause or effect?Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis.A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
P2860
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P2860
Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@ast
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@en
type
label
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@ast
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@en
prefLabel
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@ast
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@en
P2093
P2860
P1476
Granzyme B short-circuits the ...... ling by directly cleaving Bid.
@en
P2093
J A Heibein
M J Pinkoski
R C Bleackley
P2860
P304
P356
10.1128/MCB.20.11.3781-3794.2000
P407
P577
2000-06-01T00:00:00Z