The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.
about
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation stateStabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuRAU-rich elements and associated factors: are there unifying principles?Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilizationPhosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZGuardian of Genetic Messenger-RNA-Binding ProteinsRNA protein interaction in neuronsThe yeast RNA-binding protein Rbp1p modifies the stability of mitochondrial porin mRNA.Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNAMAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitmentInteraction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expressionThe proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein UDelayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signalingDecreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathwayFragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional levelMitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stabilityA novel high throughput biochemical assay to evaluate the HuR protein-RNA complex formationPhosphorylation and binding of AUF1 to the 3'-untranslated region of cardiomyocyte SERCA2a mRNAMembers of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttlingAlternate exon insertion controls selective ubiquitination and degradation of different AUF1 protein isoformsIdentification of a novel AU-rich-element-binding protein which is related to AUF1Post-transcriptional Regulation of NK Cell Activation.Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus.Post-transcriptional regulation in lymphocytes: the case of CD154MicroRNAs distinguish translational from transcriptional silencing during endotoxin tolerance.Functional characterization of the HuR:CD83 mRNA interaction.Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs.RNA-binding protein HuR is required for stabilization of SLC11A1 mRNA and SLC11A1 protein expressionHuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.Thy-1 mRNA destabilization by norepinephrine a 3' UTR cAMP responsive decay element and involves RNA binding proteins.Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase.Stimulus-specific induction of a novel nuclear factor-kappaB regulator, IkappaB-zeta, via Toll/Interleukin-1 receptor is mediated by mRNA stabilization.GroEL1, from Chlamydia pneumoniae, induces vascular adhesion molecule 1 expression by p37(AUF1) in endothelial cells and hypercholesterolemic rabbitThe p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver diseaseResveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.Different modes of interaction by TIAR and HuR with target RNA and DNANephroblastoma overexpressed (Nov) induces gremlin in ST-2 stromal cell lines by post-transcriptional mechanismsUpregulation of the host SLC11A1 gene by Clostridium difficile toxin B facilitates glucosylation of Rho GTPases and enhances toxin lethality.
P2860
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P2860
The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@ast
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@en
type
label
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@ast
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@en
prefLabel
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@ast
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@en
P2093
P2860
P1476
The 3' untranslated region of ...... e mRNA-stabilizing factor HuR.
@en
P2093
P2860
P304
P356
10.1128/MCB.21.3.721-730.2001
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P577
2001-02-01T00:00:00Z