HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay. - Wikidata - wikimedia - TriplyDB

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

http://www.wikidata.org/entity/Q34045640

about

RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage Functional interplay between RNA-binding protein HuR and microRNAs Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins.AUF1 facilitates microRNA-mediated gene silencing.Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation.p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.The molecular balancing act of p16(INK4a) in cancer and aging.The regulation of mRNA stability in mammalian cells: 2.0.Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands.Loss of CARM1 is linked to reduced HuR function in replicative senescence.The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells.HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironment MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cells LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal.The RNA-binding protein human antigen R controls global changes in gene expression during Schwann cell development.AUF1 promotes let-7b loading on Argonaute 2.β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16 NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation.Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.Essential Roles of RNA-binding Protein HuR in Activation of Hepatic Stellate Cells Induced by Transforming Growth Factor-β1 Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs.Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1 Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins.HuR maintains a replicative life span by repressing the ARF tumor suppressor.Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP).ADAR regulates RNA editing, transcript stability, and gene expression.let-7-repressesed Shc translation delays replicative senescence.Conditional knockout of the RNA-binding protein HuR in CD4⁺ T cells reveals a gene dosage effect on cytokine production Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer.AUF1 and HuR: possible implications of mRNA stability in thyroid function and disorders.The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.Posttranscriptional Gene Regulation: Novel Pathways for Glucocorticoids' Anti-inflammatory Action.HuR and post-transcriptional regulation in vascular aging.RNA-binding proteins as molecular links between cancer and neurodegeneration.

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P2860

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

http://www.wikidata.org/entity/Q34045640

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@ast

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@en

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@nl

type

label

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@ast

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@en

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@nl

prefLabel

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@ast

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@en

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@nl

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P2860

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P1433

Molecular and Cellular Biology

P1476

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.

@en

P2093

Gaier Guo

http://www.w3.org/2001/XMLSchema#string

Jie Yi

http://www.w3.org/2001/XMLSchema#string

Ming Zhan

http://www.w3.org/2001/XMLSchema#string

Na Chang

http://www.w3.org/2001/XMLSchema#string

Qinghua Cui

http://www.w3.org/2001/XMLSchema#string

Tanjun Tong

http://www.w3.org/2001/XMLSchema#string

Wengong Wang

http://www.w3.org/2001/XMLSchema#string

Xinwen Liu

http://www.w3.org/2001/XMLSchema#string

Yongfeng Shang

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.

HuR regulates p21 mRNA stabilization by UV light

Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps

HuR recruits let-7/RISC to repress c-Myc expression

Protein ligands to HuR modulate its interaction with target mRNAs in vivo

The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation

Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

Involvement of microRNA in AU-rich element-mediated mRNA instability

P304

3875-3886

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scholarly article

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10.1128/MCB.00169-10

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P407

P433

15

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P478

30

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P577

2010-05-24T00:00:00Z

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20498276

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P932

2916395

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