Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype.
about
Host cell protein dynamics in the supernatant of a mAb producing CHO cell line.Elucidation of the CHO Super-Ome (CHO-SO) by Proteoinformatics.Proteomic analysis of Chinese hamster ovary cellsAn 'omics approach towards CHO cell engineering.Proteins improving recombinant antibody production in mammalian cells.The 'Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity.An ultra scale-down approach identifies host cell protein differences across a panel of mAb producing CHO cell line variants.Screening and assessment of performance and molecule quality attributes of industrial cell lines across different fed-batch systems.Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity.Bioreactor environment-sensitive sentinel genes as novel metrics for cell culture scale-down comparability.The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process.Novel Cell-Ess ® supplement used as a feed or as an initial boost to CHO serum free media results in a significant increase in protein yield and production.Proteomic differences in recombinant CHO cells producing two similar antibody fragments.Two-Dimensional Gel Electrophoresis and 2D-DIGE.A quantitative proteomic analysis of cellular responses to high glucose media in Chinese hamster ovary cells.Recovery of Chinese hamster ovary host cell proteins for proteomic analysis.Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.Genomic analysis of a hybridoma batch cell culture metabolic status in a standard laboratory 5 L bioreactor.
P2860
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P2860
Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype.
description
2011 nî lūn-bûn
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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
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2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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name
Sustained productivity in reco ...... r a process-related phenotype.
@ast
Sustained productivity in reco ...... r a process-related phenotype.
@en
type
label
Sustained productivity in reco ...... r a process-related phenotype.
@ast
Sustained productivity in reco ...... r a process-related phenotype.
@en
prefLabel
Sustained productivity in reco ...... r a process-related phenotype.
@ast
Sustained productivity in reco ...... r a process-related phenotype.
@en
P2093
P2860
P356
P1433
P1476
Sustained productivity in reco ...... r a process-related phenotype.
@en
P2093
Colin Clarke
Finbar O'Sullivan
Joanne Keenan
Mark Leonard
Mark W Melville
Martin Clynes
Michael Henry
Niall Barron
Padraig Doolan
Patrick Gammell
P2860
P2888
P356
10.1186/1472-6750-11-78
P577
2011-07-24T00:00:00Z
P5875
P6179
1023071959