Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species.
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Essential gene identification and drug target prioritization in Aspergillus fumigatusSREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatusDiscovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossingGenetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus's Role in VirulenceTriazole Resistance in Aspergillus Species: An Emerging Problem.Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.Development of a novel multiplex DNA microarray for Fusarium graminearum and analysis of azole fungicide responses.Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanismAnidulafungin and voriconazole in invasive fungal disease: pharmacological data and their use in combination.Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene.Fungal PDR transporters: Phylogeny, topology, motifs and function.Differences in interactions between azole drugs related to modifications in the 14-alpha sterol demethylase gene (cyp51A) of Aspergillus fumigatus.Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.Endoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus.First detection of TR46/Y121F/T289A and TR34/L98H alterations in Aspergillus fumigatus isolates from azole-naive patients in Denmark despite negative findings in the environment.Antifungal triazoles and polymorphonuclear leukocytes synergize to cause increased hyphal damage to Scedosporium prolificans and Scedosporium apiospermum.Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.Aspergillus fumigatus C-5 sterol desaturases Erg3A and Erg3B: role in sterol biosynthesis and antifungal drug susceptibility.Drug strategies targeting CYP51 in neglected tropical diseasesMutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase.Aspergillus fumigatus strains with mutations in the cyp51A gene do not always show phenotypic resistance to itraconazole, voriconazole, or posaconazole.Composite survival index to compare virulence changes in azole-resistant Aspergillus fumigatus clinical isolates.Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance.The strength of synergistic interaction between posaconazole and caspofungin depends on the underlying azole resistance mechanism of Aspergillus fumigatus.Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.SREBP-dependent triazole susceptibility in Aspergillus fumigatus is mediated through direct transcriptional regulation of erg11A (cyp51A).Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, JapanRapid induction of multiple resistance mechanisms in Aspergillus fumigatus during azole therapy: a case study and review of the literature.Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome SequencingMultiple cyp51A-based mechanisms identified in azole-resistant isolates of Aspergillus fumigatus from China.Triazole Susceptibilities in Thermotolerant Fungal Isolates from Outdoor Air in the Seoul Capital Area in South Korea.Co-Occurrence of Two Allelic Variants of CYP51 in Erysiphe necator and Their Correlation with Over-Expression for DMI Resistance.Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.Time of incubation for antifungal susceptibility testing of Aspergillus fumigatus: can MIC values be obtained at 24 hours?Quantitative Analysis of Single-Nucleotide Polymorphism for Rapid Detection of TR34/L98H- and TR46/Y121F/T289A-Positive Aspergillus fumigatus Isolates Obtained from Patients in Iran from 2010 to 2014.Rapid detection of triazole antifungal resistance in Aspergillus fumigatus.Molecular Characterization of a Voriconazole-Resistant, Posaconazole-Susceptible Aspergillus fumigatus Isolate in a Lung Transplant Recipient in the United States.The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility.Breakthrough Aspergillus fumigatus and Candida albicans double infection during caspofungin treatment: laboratory characteristics and implication for susceptibility testing.
P2860
Q28469156-F4E869E6-D3A5-4395-BC47-10588DA30C96Q28478226-BE1273E6-E308-4444-8A8E-AA1E4A57930FQ28485433-7B7BE475-5C8F-4789-AE75-15446B67482EQ28546712-0E73F48B-DE64-4A3F-8363-F0069B788B61Q30235566-A9015DE0-F6BA-4797-9E00-B1B658493DE5Q30318077-84E903DA-7DEB-465E-9035-84D439755EB8Q30318491-1C815E5E-EBCF-4415-B1FF-307E1C671F2AQ30853962-6B21052B-1781-4898-852A-531074F186A2Q33490772-AF1A4CAD-F8B7-4A89-BF75-FDEC01D9E893Q33613758-A7636299-F9F4-427A-849C-0170DA56F278Q33624643-E75FF717-7DE7-4E5D-8A7D-FFC396AC6334Q33770230-C0DDDB3C-E3E0-4101-9341-5A7960B934F2Q33836567-12F14B16-FC87-4ED9-AC92-4C140F615F50Q33956119-58184F0A-055E-48F9-9D85-D9E6AB0294D7Q34057414-18FAB74B-F50E-4E78-AFAC-AAEF2B2FA176Q34109768-B069D0B5-6B66-4045-9EC3-9909F0DB9CCEQ34151112-30893399-27D9-4659-AC38-470D5DA4976FQ34290082-0BB7C863-33B2-420F-8DFE-5138A38F3484Q34352270-41B785A6-F49B-4B5C-BFC1-85226F238776Q34622554-CFB77C32-5CFA-4754-9132-DA9050D829B3Q34823914-00E9B0D0-95DE-4EB9-AEE0-17A9DCA9B40DQ34933141-666EAB6D-FBAD-41F1-9A11-DBB21C0D849BQ34977071-27EA76F1-4EFD-4B96-84C9-7E6CF9755AD2Q35066763-757686B2-B9B5-4B8C-80CC-3B1E8217DD67Q35076940-44EB4397-63C6-4946-8094-B6DDE627D5A5Q35124469-7041A72B-495A-4176-B0E1-C64D5C468E76Q35666510-12D70A39-9D8F-4E59-BF9A-30625E3AF218Q35666518-D72AED11-2FE4-4D34-8ECD-53FBA93997F8Q35666591-FC4C8ED6-16B5-4573-B8D7-34705DF2CEE4Q35676292-1F5FCBDC-027E-4357-896E-830918F85ACCQ35746043-EF770099-7FC3-46C2-83C3-D07F377B65EEQ35787585-1E536F2A-6075-40C9-841F-8150AE5B6BDFQ35912952-43112C75-C27E-47AD-BD7B-43C251F264CCQ36093075-4F481114-708D-4799-A82F-C56284580AEFQ36313161-A5B6879D-8500-4E85-9BD5-F28B23DEB7BCQ36439193-A97A7E98-0AE3-4B26-8721-6A93B94C7A0EQ36539892-733ED1B5-2F85-467A-ADBA-9171211D060BQ36571881-D7B792D0-404A-4F08-9E93-FE0C638B36A2Q36687065-FCE8AE20-70C8-435D-87A1-66A75A745DF4Q37115801-D10F3617-34EE-45A9-B01D-83A880E05257
P2860
Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Identification of two differen ...... and other Aspergillus species.
@ast
Identification of two differen ...... and other Aspergillus species.
@en
type
label
Identification of two differen ...... and other Aspergillus species.
@ast
Identification of two differen ...... and other Aspergillus species.
@en
prefLabel
Identification of two differen ...... and other Aspergillus species.
@ast
Identification of two differen ...... and other Aspergillus species.
@en
P2093
P2860
P921
P1476
Identification of two differen ...... and other Aspergillus species.
@en
P2093
J L Rodriguez-Tudela
M Cuenca-Estrella
T M Diaz-Guerra
P2860
P304
P356
10.1128/JCM.39.7.2431-2438.2001
P407
P577
2001-07-01T00:00:00Z