Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis
about
A mutation in Escherichia coli DNA gyrase conferring quinolone resistance results in sensitivity to drugs targeting eukaryotic topoisomerase IIEvaluation of susceptibility testing to detect fluoroquinolone resistance mechanisms in Streptococcus pneumoniaeRole of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis.Quinolone molecular structure-activity relationships: what we have learned about improving antimicrobial activity.Antimicrobial drug use and resistance among respiratory pathogens in the community.Role of the extended alpha4 domain of Staphylococcus aureus gyrase A protein in determining low sensitivity to quinolones.NorC, a new efflux pump regulated by MgrA of Staphylococcus aureus.Replacement of ParC alpha4 helix with that of GyrA increases the stability and cytotoxicity of topoisomerase IV-quinolone-DNA ternary complexes.Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions.First characterization of fluoroquinolone resistance in Streptococcus suis.Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone.Mechanisms of drug resistance: quinolone resistance.Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance.Quinolone-mediated bacterial death.Quinolones: action and resistance updated.Mechanism of quinolone action and resistance.Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance.DNA replication proteins as potential targets for antimicrobials in drug-resistant bacterial pathogens.A brief history of antibiotics and select advances in their synthesis.A Novel Method for the Synthesis of (99m)Tc-Ofloxacin Kits Using D-Penicillamine as Coligand and Their Application as Infection Imaging Agent.Antimicrobial peptides as infection imaging agents: better than radiolabeled antibiotics.Comparison of in vitro activities of fluoroquinolone-like 2,4- and 1,3-diones.(99m) Tc-tricabonyl labeling of ofloxacin and its biological evaluation in Staphylococcus aureus as an infection imaging agent.Technetium-99m Tricarbonyl Labeled a Broad-spectrum Quinolone as a Specific Imaging Agent in Infection Diseases.Effect of anaerobic growth on quinolone lethality with Escherichia coli.Global transcriptome analysis of the responses of a fluoroquinolone-resistant Streptococcus pneumoniae mutant and its parent to ciprofloxacin.Staphylococcus aureus gyrase-quinolone-DNA ternary complexes fail to arrest replication fork progression in vitro. Effects of salt on the DNA binding mode and the catalytic activity of S. aureus gyrase.A recA-LexA-dependent pathway mediates ciprofloxacin-induced fibronectin binding in Staphylococcus aureus.Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance.Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities.Activities of gyrase and topoisomerase IV on positively supercoiled DNA.Synthesis and Antibacterial Activity of Some Novel 4-Oxopyrido[2,3-a]phenothiazines
P2860
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P2860
Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@ast
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@en
type
label
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@ast
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@en
prefLabel
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@ast
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@en
P2093
P2860
P1476
Selective targeting of topoiso ...... ed inhibition of DNA synthesis
@en
P2093
P2860
P304
P356
10.1128/AAC.44.8.2160-2165.2000
P407
P50
P577
2000-08-01T00:00:00Z