Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways - Wikidata - wikimedia - TriplyDB

Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways

Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways

http://www.wikidata.org/entity/Q33984585

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ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein Targeting the tumor microenvironment: JAK-STAT3 signaling Regulation of STATs by polycystin-1 and their role in polycystic kidney disease Experimental therapies and ongoing clinical trials to slow down progression of ADPKD Screening approaches to generating STAT inhibitors: Allowing the hits to identify the targets Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells.Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease Vasopressin and disruption of calcium signalling in polycystic kidney disease.Emerging role of autophagy in kidney function, diseases and aging STAT3 Signaling in Polycystic Kidney Disease Four clinically utilized drugs were identified and validated for treatment of adrenocortical cancer using quantitative high-throughput screening The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations Cutaneous plasmablastic lymphoma in an immunocompetent patient with long-term pyrimethamine use for essential thrombocythemia: a case report and literature review.Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer.Primary cilia and kidney injury: current research status and future perspectives Autocrine IL-10 activation of the STAT3 pathway is required for pathological macrophage differentiation in polycystic kidney disease Polycystic kidney disease in 2011: Connecting the dots toward a polycystic kidney disease therapy.Cancer stem cells, microRNAs, and therapeutic strategies including natural products.New treatments for autosomal dominant polycystic kidney disease STAT signaling in the pathogenesis and treatment of myeloid malignancies.Strategies targeting cAMP signaling in the treatment of polycystic kidney disease.Genetic Interactions of STAT3 and Anticancer Drug Development.JAK inhibition and progressive kidney disease.STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy.The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations.The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1.Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.Autophagy and Tubular Cell Death in the Kidney.Combination drug versus monotherapy for the treatment of autosomal dominant polycystic kidney disease.Primary Cilia in Cystic Kidney Disease.Src family kinases in chronic kidney disease.Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease.Extracellular Signal-Regulated Kinase 1/2 Regulates Mouse Kidney Injury Molecule-1 Expression Physiologically and Following Ischemic and Septic Renal Injury.Targeting Oncogenic Transcription Factors: Therapeutic Implications of Endogenous STAT Inhibitors.The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer.Identification of Targets of Interleukin-13 and Signal Transducer and Activator of Transcription-6 (STAT6) Signaling in Polycystic Kidney Disease.The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells.

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P2860

Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways

http://www.wikidata.org/entity/Q33984585

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

@ast

Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

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type

label

Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

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Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

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prefLabel

Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

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Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

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P1433

Human Molecular Genetics

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Pyrimethamine inhibits adult p ...... lating STAT signaling pathways

@en

P2093

Ayumi Takakura

http://www.w3.org/2001/XMLSchema#string

Benjamin D Humphreys

http://www.w3.org/2001/XMLSchema#string

David A Frank

http://www.w3.org/2001/XMLSchema#string

Erik A Nelson

http://www.w3.org/2001/XMLSchema#string

Jing Zhou

http://www.w3.org/2001/XMLSchema#string

Kambiz Zandi-Nejad

http://www.w3.org/2001/XMLSchema#string

Nadeem Haque

http://www.w3.org/2001/XMLSchema#string

P2860

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

A road map for those who don't know JAK-STAT

PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.

Signal transduction and transcriptional adaptation in embryonic heart development and during myocardial hypertrophy.

Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease.

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4143-4154

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scholarly article

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10.1093/HMG/DDR338

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21

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20

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2011-08-05T00:00:00Z

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51552156

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21821671

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P932

3188991

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