Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis. - Wikidata - wikimedia - TriplyDB

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis.

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis.

http://www.wikidata.org/entity/Q33999281

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Iron, hepcidin, and the metal connection Clinical review: sepsis and septic shock--the potential of gene arrays Zinc deficiency primes the lung for ventilator-induced injury Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-kappaB Zinc in innate and adaptive tumor immunity.A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission.Zinc regulates the acute phase response and serum amyloid A production in response to sepsis through JAK-STAT3 signaling Intestinal epithelium is more susceptible to cytopathic injury and altered permeability than the lung epithelium in the context of acute sepsis.Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen.Impact of zinc metabolism on innate immune function in the setting of sepsis.A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis Zinc and cancer: implications for LIV-1 in breast cancer.Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis.Zinc dyshomeostasis during polymicrobial sepsis in mice involves zinc transporter Zip14 and can be overcome by zinc supplementation Hemorrhagic shock and surgical stress alter distribution of labile zinc within high- and low-molecular-weight plasma fractions.Persistent low serum zinc is associated with recurrent sepsis in critically ill patients - A pilot study.Functional role of intracellular labile zinc in pulmonary endothelium.Increased inflammatory response in aged mice is associated with age-related zinc deficiency and zinc transporter dysregulation.Zinc-deficient diet aggravates ventilation-induced lung injury in rats.Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.Genome-wide expression profiling in pediatric septic shock.ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB.Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis.Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism.Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis.Mechanisms and regulation of the gene-expression response to sepsis.Genetics and genomics in pediatric septic shock.Zinc signals and immune function.Prevalence of systemic inflammation and micronutrient imbalance in patients with complex abdominal hernias.Multiple impacts of zinc on immune function.Impact of Zinc Supplementation on the Clinical Outcomes of Patients with Severe Head Trauma: A Double-Blind Randomized Clinical Trial.Role of Zinc in the Development/Progression of Alcoholic Liver Disease.Metabolism, Metabolomics, and Nutritional Support of Patients with Sepsis.Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair Zinc depletion regulates the processing and secretion of IL-1β.Immune and metabolic responses in early and late sepsis during mild dietary zinc restriction.Zinc supplementation leads to immune modulation and improved survival in a juvenile model of murine sepsis.

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P2860

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis.

http://www.wikidata.org/entity/Q33999281

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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Zinc deficiency increases orga ...... model of polymicrobial sepsis.

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Zinc deficiency increases orga ...... model of polymicrobial sepsis

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Daren L Knoell

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P2860

The epidemiology of sepsis in the United States from 1979 through 2000

Superoxide dismutase: improved assays and an assay applicable to acrylamide gels

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome.

Zinc homeostasis in humans.

Mammalian zinc transport, trafficking, and signals.

Sepsis and evolution of the innate immune response.

The alcoholic lung: epidemiology, pathophysiology, and potential therapies.

Effects of zinc deficiency and pneumococcal surface protein a immunization on zinc status and the risk of severe infection in mice.

Zinc: health effects and research priorities for the 1990s.

Abrogation of nuclear factor-kappaB activation is involved in zinc inhibition of lipopolysaccharide-induced tumor necrosis factor-alpha production and liver injury

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