The mode of action of nicotine and curari, determined by the form of the contraction curve and the method of temperature coefficients.
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Open channel and competitive block of the embryonic form of the nicotinic receptor of mouse myotubes by (+)-tubocurarineLong-lasting target binding and rebinding as mechanisms to prolong in vivo drug actionA Philosophical Framework for Integrating Systems Pharmacology Models Into PharmacometricsA three-parameter two-state model of receptor function that incorporates affinity, efficacy, and signal amplification.Modeling and validation of autoinducer-mediated bacterial gene expression in microfluidic environmentsWavelet analysis of nonstationary fluctuations of Monte Carlo-simulated excitatory postsynaptic currents.The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptorsFlapping loops: roles for hinges in a ligand-binding domain of the nicotinic receptor.Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptorsAgonist-activated ion channels.The role of kinetic context in apparent biased agonism at GPCRs.Functionomics: the analysis of a postgenomic concept on the basis of pregenomic pharmacological studies in smooth muscle.Harms from medicines: inevitable, in error or intentional.Time-scale separation--Michaelis and Menten's old idea, still bearing fruit.Cato Guldberg and Peter Waage, the history of the Law of Mass Action, and its relevance to clinical pharmacology.TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy.Theory-based pharmacokinetics and pharmacodynamics of S- and R-warfarin and effects on international normalized ratio: influence of body size, composition and genotype in cardiac surgery patients.The effect of tubocurarine competition on the kinetics of agonist action on the nicotinic receptor.On the calcium receptor that mediates depolarization-secretion coupling at cholinergic motor nerve terminalsThe kinetics of inhibition of rat recombinant heteromeric alpha1beta glycine receptors by the low-affinity antagonist SR-95531.Inhibitory glutamate receptor channels.Diffusion of drugs through stationary water layers as the rate limiting process in their action at membrane receptors.The muscarinic receptor of chick embryo cells: correlation between ligand binding and calcium mobilization.The influence of the gamma 2L subunit on the modulation of responses to GABAA receptor activation.Alpha 4-2 beta 2 and other nicotinic acetylcholine receptor subtypes as targets of psychoactive and addictive drugsQuantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M3 receptor.A golden approach to ion channel inhibitionBiology is more theoretical than physics.Stimulation of histone deacetylase activity by metabolites of intermediary metabolismKinetic constants of the acetylcholine (ACh) receptor reaction deduced from the rise in open probability after steps in ACh concentration.Using Nature's "Tricks" To Rationally Tune the Binding Properties of Biomolecular Receptors.Fourth gaddum memorial lecture, school of pharmacy, university of london, january 1973.Desensitization and models of receptor-channel activation.Inhibitory glutamate receptor channels in cultured lobster stomatogastric neurons.A model of T cell-target interaction leading to lymphokine release.Sodium currents in Schwann cells from myelinated and non-myelinated nerves of neonatal and adult rabbits.The pharmacological actions of polymethylene bistrimethylammonium salts.Drug receptors and their function.Synthesis and characterization of neurotensin analogues for structure/activity relationship studies. Acetyl-neurotensin-(8--13) is the shortest analogue with full binding and pharmacological activities.The active principles of the branchlet and hook of Uncaria sinensis Oliv. examined with a 5-hydroxytryptamine receptor binding assay.
P2860
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P2860
The mode of action of nicotine and curari, determined by the form of the contraction curve and the method of temperature coefficients.
description
1909 nî lūn-bûn
@nan
1909 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1909 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1909年の論文
@ja
1909年論文
@yue
1909年論文
@zh-hant
1909年論文
@zh-hk
1909年論文
@zh-mo
1909年論文
@zh-tw
1909年论文
@wuu
name
The mode of action of nicotine ...... d of temperature coefficients.
@ast
The mode of action of nicotine ...... d of temperature coefficients.
@en
type
label
The mode of action of nicotine ...... d of temperature coefficients.
@ast
The mode of action of nicotine ...... d of temperature coefficients.
@en
prefLabel
The mode of action of nicotine ...... d of temperature coefficients.
@ast
The mode of action of nicotine ...... d of temperature coefficients.
@en
P1476
The mode of action of nicotine ...... d of temperature coefficients.
@en
P2093
P304
P356
10.1113/JPHYSIOL.1909.SP001344
P407
P577
1909-12-01T00:00:00Z