Cellular functions of the BRCA tumour-suppressor proteins.
about
BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancersRad52 inactivation is synthetically lethal with BRCA2 deficiencyIncreased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary adenocarcinomasChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageSUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damageHomologs of breast cancer genes in plantsGenetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized MedicineOvarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalitiesBRCA1 and BRCA2 missense variants of high and low clinical significance influence lymphoblastoid cell line post-irradiation gene expressionRecent advances in the research for the homolog of breast cancer associated gene AtROW1 in higher plants.Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma.Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells.Significance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancerEmergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms.Toward classification of BRCA1 missense variants using a biophysical approach.Enhanced sensitivity to cisplatin and gemcitabine in Brca1-deficient murine mammary epithelial cells.Initiation of DNA interstrand cross-link repair in mammalian cells.miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana.Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).E3 ubiquitin ligases in ErbB receptor quantity control.Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations.BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood.Risk factors for ovarian cancer: an overview with emphasis on hormonal factors.Skp2 overexpression is associated with loss of BRCA2 protein in human prostate cancer.Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancerDecreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1-containing complexPersonalized medicine: new genomics, old lessonsMicroenvironment and pathogenesis of epithelial ovarian cancerBRCA1 tumor suppressor network: focusing on its tail.Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older women.Homologous Recombination Defective Arabidopsis Mutants Exhibit Enhanced Sensitivity to Abscisic Acid.p21 promotes error-free replication-coupled DNA double-strand break repairIdentification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?Common variants of Drosophila melanogaster Cyp6d2 cause camptothecin sensitivity and synergize with loss of Brca2.Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriersSuccessful design and conduct of genome-wide association studies.Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteins
P2860
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P2860
Cellular functions of the BRCA tumour-suppressor proteins.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cellular functions of the BRCA tumour-suppressor proteins.
@ast
Cellular functions of the BRCA tumour-suppressor proteins.
@en
Cellular functions of the BRCA tumour-suppressor proteins.
@nl
type
label
Cellular functions of the BRCA tumour-suppressor proteins.
@ast
Cellular functions of the BRCA tumour-suppressor proteins.
@en
Cellular functions of the BRCA tumour-suppressor proteins.
@nl
prefLabel
Cellular functions of the BRCA tumour-suppressor proteins.
@ast
Cellular functions of the BRCA tumour-suppressor proteins.
@en
Cellular functions of the BRCA tumour-suppressor proteins.
@nl
P356
P1476
Cellular functions of the BRCA tumour-suppressor proteins.
@en
P2093
Boulton SJ
P304
P356
10.1042/BST0340633
P577
2006-11-01T00:00:00Z