ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells
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The power to reduce: pyridine nucleotides--small molecules with a multitude of functionsThe hunt for an alternate way to generate NAADP. Focus on "NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells"Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathologyEvidence of a new phosphoryl transfer system in nucleotide metabolismMolecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin.A multifunctional enzyme adds to its repertoire.NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes.The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responsesThe CD38/CD157 mammalian gene family: An evolutionary paradigm for other leukocyte surface enzymes.Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation.The signaling protein CD38 is essential for early embryonic development.The diadenosine homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-Tooth type 1A.ADP-ribosyl-N₃: A Versatile Precursor for Divergent Syntheses of ADP-ribosylated Compounds.Diadenosine diphosphate (Ap₂A) delays neutrophil apoptosis via the adenosine A2A receptor and cAMP/PKA pathway.Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR
P2860
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P2860
ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@ast
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@en
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@nl
type
label
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@ast
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@en
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@nl
prefLabel
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@ast
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@en
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@nl
P2093
P2860
P50
P356
P1476
ADP-ribosyl cyclases generate ...... ic activity on mammalian cells
@en
P2093
Andrea Armirotti
Antonio De Flora
Gianluca Damonte
Giovanna Basile
Luisa Franco
Orazio Taglialatela-Scafati
P2860
P304
14509-14514
P356
10.1073/PNAS.0503691102
P407
P577
2005-09-19T00:00:00Z