The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses - Wikidata - wikimedia - TriplyDB

The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses

The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses

http://www.wikidata.org/entity/Q36436005

about

Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming SIRTain regulators of premature senescence and accelerated aging Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas Sirtuins in metabolism, DNA repair and cancer Sirtuin deacylases: a molecular link between metabolism and immunity Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients.SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC.1H NMR Metabolomics Reveals Association of High Expression of Inositol 1, 4, 5 Trisphosphate Receptor and Metabolites in Breast Cancer Patients When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells Histone deacetylases and mechanisms of regulation of gene expression Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.A miR-34a-SIRT6 axis in the squamous cell differentiation network Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6 The emerging and diverse roles of sirtuins in cancer: a clinical perspective.Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway.Sirtuins and cancer: new insights and cell signaling.TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migration Sirt6 regulates dendritic cell differentiation, maturation, and function.Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation.Astragaloside IV sensitizes non-small cell lung cancer cells to gefitinib potentially via regulation of SIRT6.Sirtuin SIRT6 suppresses cell proliferation through inhibition of Twist1 expression in non-small cell lung cancer.SIRT6: Novel Mechanisms and Links to Aging and Disease.Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin.Sirtuin 6 contributes to migration and invasion of osteosarcoma cells via the ERK1/2/MMP9 pathway.The guardian: metabolic and tumour-suppressive effects of SIRT6.SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts.MicroRNA-186 suppresses lung cancer progression by targeting SIRT6.Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling.Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.Gene expressions of TRP channels in glioblastoma multiforme and relation with survival.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway.Low Rap1-interacting factor 1 and sirtuin 6 expression predict poor outcome in radiotherapy-treated Hodgkin lymphoma patients.TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma.

P2860

Q26991931-A54EAC69-8016-478A-B729-810D4F97371E Q26997358-943CACA9-A1C0-4380-91B7-A885EBD83CFE Q27001553-F1DA79FA-B288-4B14-9D77-BEE16D3B6478 Q27021883-469A972D-F4C7-4694-ACDA-03A729086549 Q28070892-83F87E53-5C44-4EE8-B61B-81968CD472A4 Q28283588-B0A7F97F-B045-4B35-BFAE-9E147B6C4A83 Q28543464-46EAAB59-03E0-44D2-B6C1-E943D1E7489D Q30402082-C6EC8E45-2CD8-481F-96A3-4DAA43A441E7 Q34049423-35D7D170-A513-45C1-8CAC-BEF43ABB6646 Q35677046-61E8E000-90FF-416D-89D3-CE2AAC2C73B4 Q36185669-F47DF72E-0B52-435E-8B9B-F8688B4B267C Q36245590-A9657027-4CA4-4292-BF2A-0B3B1A03D527 Q36442945-AE887527-2C34-406C-B04D-D70AE762B097 Q36689434-D8515073-7437-4B54-8AA3-58499E4A70CD Q36734390-EFB727D1-BA0B-4219-B12F-AF9AB9E104BB Q36771997-898E88EB-38FE-4E6B-BD80-C1BA06CD973A Q37101911-09DC10EB-BABB-49E5-9B11-19C888EA3A8D Q37163041-26A316F0-FAA1-4384-A3BB-AA187BE88F4E Q37231067-12376E46-DDB5-4A56-944F-07524FEE03A4 Q37457884-274D6F4F-FE66-4DEE-A362-45718650D6B8 Q38168292-D6925ADE-2220-4182-80AE-27FCF235D348 Q38203918-3DD532DF-FCB9-49BB-AACE-8BCD3FA0158D Q38579945-9AED7FB9-42AE-41A9-9492-F0CC11C4276E Q38614956-ADD676DE-8BEA-4377-9388-3D22609A69C9 Q38819679-A7BD39AE-EB3A-49FC-800C-BF7BAA63EDC3 Q38958874-8458BEC3-117E-48AB-980C-156A4848C5B6 Q39005741-ADB8F286-705B-49BC-BDEE-21072F79DD9A Q39104113-E8308E0B-73CC-4406-A639-C5D09C024961 Q39195646-B0992991-050A-4633-9E37-E451B8A229B5 Q41627701-B87528DA-C111-4985-A15B-4C1BC5C393CE Q42135099-EA2A875F-35F7-434A-BD38-FA3E4BE4729F Q42455903-F2757F2C-0A74-4D74-AA06-5FB71B40BBC0 Q47361771-F30242BD-0707-4729-A90B-51BFEE016239 Q50035013-9E17FE60-24BD-4BC8-950D-A74E5781950B Q50134165-3D4B5B5E-7C66-42A6-9FF7-1C834511C6D1 Q51489436-A0A41982-85BD-4370-ABEB-53721EE22FCE Q51825149-740D8DC3-68B0-45AA-B14F-771ABFD59936 Q52670082-06565B0D-73E8-4496-869C-F398CBFA35C6 Q53183757-E9703256-71D5-47C7-8FF0-FC6FF1E90694 Q55004181-048524CE-ABBF-4A05-B224-4A8D20A59C1D

P2860

The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses

http://www.wikidata.org/entity/Q36436005

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@ast

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@en

type

label

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@ast

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@en

prefLabel

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@ast

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@en

P1433

Q36436005-91F92A7B-3566-45CB-88FF-139165D40189

P1476

Q36436005-12C3962B-5B57-4D4C-BAB7-919589781E4A

P2093

Q36436005-14ABEADA-8F59-49E8-A2C3-D3DA0BC1CCB8

Q36436005-218780EB-88E1-401D-975E-BB76ABEF5CD3

Q36436005-23F3C0A0-39B8-4AA3-AADC-B6376B0AA602

Q36436005-25FEE798-D430-4B91-A25C-3DFA1DFDB627

Q36436005-42FBB5B8-A492-40C4-BE4F-D1FF3E8B6FC7

Q36436005-4E85984F-4D5D-48F1-A672-EB431BAE61FE

Q36436005-6661AABE-A9B8-4C60-A81E-A4294F5A428D

Q36436005-7A0F25F9-386E-4CF3-981B-DDB379F3B871

Q36436005-7C83F901-4DEC-4BE8-A3CC-860C962C2976

Q36436005-9386680E-AB7F-44E9-B005-5324D082D694

P2860

Q36436005-010BF42F-A2AC-4992-8FB2-2B95133347EC

Q36436005-040AE202-68C5-4FE8-8839-761D69F1C29C

Q36436005-0908FB28-22B6-44D7-B2F1-6B282B9ABEE1

Q36436005-0EB9CC2F-9DF7-4335-8A3C-A45E5AF6FCA6

Q36436005-11202ECE-2FEC-4CD2-9E98-95B774A71D13

Q36436005-143BFEB8-4D5A-4365-BC06-D529AF406646

Q36436005-15A99220-C0EE-4340-9265-9BDC954B04EF

Q36436005-188834C2-ADAC-4B5C-9624-4E9986B852F5

Q36436005-18B23E6A-BA91-4F5B-A1C4-0A10D07EC797

Q36436005-1C0D4CE3-6605-41F3-ACD2-00AB8A0ACB33

P304

Q36436005-BF2A9885-28EE-4B87-9CB3-C9ED342F037C

P31

Q36436005-9A4AF244-AAF4-437A-BADE-734318AC23B3

P356

Q36436005-E8D4568B-9554-4069-BB03-85231B936480

P407

Q36436005-439D8F57-8385-41D5-B76E-A51561C9EF1A

P433

Q36436005-C469D392-E9B0-4406-88E1-7E430E95C7EF

P478

Q36436005-2C94038E-E2F8-4201-A0DC-BE076532881B

P50

Q36436005-25D8DB94-EF1A-4FD8-8E4C-D03D6AAFEC16

Q36436005-9C172B03-E2F2-406D-A5A3-66636464CADB

P577

Q36436005-8B918245-3B53-4F01-8945-90D1D3B6B805

P5875

Q36436005-CFB089B3-C70E-44FB-AF57-2F1A10966917

P698

Q36436005-ED1B9DFA-158F-4CCA-AD9D-07CE319F24D7

P932

Q36436005-E689910B-75F4-4F1F-AC8E-00F9C8B29A0C

P356

JBC.M112.405837

P1433

Journal of Biological Chemistry

P1476

The NAD+-dependent histone dea ...... s by regulating Ca2+ responses

@en

P2093

Alberto Ballestrero

http://www.w3.org/2001/XMLSchema#string

Alessandro Poggi

http://www.w3.org/2001/XMLSchema#string

Alessia Grozio

http://www.w3.org/2001/XMLSchema#string

Alessio Nencioni

http://www.w3.org/2001/XMLSchema#string

Debora Soncini

http://www.w3.org/2001/XMLSchema#string

Denise Lasigliè

http://www.w3.org/2001/XMLSchema#string

Franco Patrone

http://www.w3.org/2001/XMLSchema#string

Gabriele Zoppoli

http://www.w3.org/2001/XMLSchema#string

Georg Feldmann

http://www.w3.org/2001/XMLSchema#string

Giovanna Basile

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular Pathways Linking Inflammation and Cancer

Hallmarks of Cancer: The Next Generation

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

Human SIRT6 promotes DNA end resection through CtIP deacetylation

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer.

Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

Inflammation and cancer

P304

40924-40937

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M112.405837

http://www.w3.org/2001/XMLSchema#string

P407

P433

49

http://www.w3.org/2001/XMLSchema#string

P478

287

http://www.w3.org/2001/XMLSchema#string

P50

Santina Bruzzone

P577

2012-10-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

232534790

http://www.w3.org/2001/XMLSchema#string

P698

23086953

http://www.w3.org/2001/XMLSchema#string

P932

3510797

http://www.w3.org/2001/XMLSchema#string