The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells. - Wikidata - wikimedia - TriplyDB

The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells.

The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells.

http://www.wikidata.org/entity/Q34000528

about

Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription Novel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2 RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression Core binding factor β (CBFβ) is retained in the midbody during cytokinesis CBFβ and the leukemogenic fusion protein CBFβ-SMMHC associate with mitotic chromosomes to epigenetically regulate ribosomal genes FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development.Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin.Transforming growth factor beta signaling in adult cardiovascular diseases and repair.Transcriptional regulation of microRNA-100, -146a, and -150 genes by p53 and NFκB p65/RelA in mouse striatal STHdh(Q7)/ Hdh(Q7) cells and human cervical carcinoma HeLa cells.Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer.Silencing of RUNX2 enhances gemcitabine sensitivity of p53-deficient human pancreatic cancer AsPC-1 cells through the stimulation of TAp63-mediated cell death.The influence of genetic ancestry and ethnicity on breast cancer survival associated with genetic variation in the TGF-β-signaling pathway: The Breast Cancer Health Disparities Study.Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells.The RUNX family in breast cancer: relationships with estrogen signaling.The Emerging Roles of RUNX Transcription Factors in Epithelial-Mesenchymal Transition.Runx Genes in Breast Cancer and the Mammary Lineage.Roles of RUNX in Hypoxia-Induced Responses and Angiogenesis.Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity.Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations.

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P2860

The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells.

http://www.wikidata.org/entity/Q34000528

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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type

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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The Runx transcriptional co-ac ...... vasion of breast cancer cells.

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1476-4598-9-171

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Molecular Cancer

P1476

The Runx transcriptional co-ac ...... vasion of breast cancer cells.

@en

P2093

Cesar Lopez-Camacho

http://www.w3.org/2001/XMLSchema#string

Daniel Mendoza-Villanueva

http://www.w3.org/2001/XMLSchema#string

Paul Shore

http://www.w3.org/2001/XMLSchema#string

Wensheng Deng

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P2860

Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

CBFbeta is a facultative Runx partner in the sea urchin embryo.

Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta

Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

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1476-4598-9-171

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171

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scholarly article

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10.1186/1476-4598-9-171

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9

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2010-06-30T00:00:00Z

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44887931

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1036089517

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20591170

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2905338

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