Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells
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The canonical BMP signaling pathway plays a crucial part in stimulation of dentin sialophosphoprotein expression by BMP-2Targeting tumor-stromal interactions in bone metastasisCell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by HypoxiaRole of RUNX2 in Breast CarcinogenesisRunx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasionRUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.Applications of transgenics in studies of bone sialoprotein.The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells.Homeobox transcription factor muscle segment homeobox 2 (Msx2) correlates with good prognosis in breast cancer patients and induces apoptosis in vitro.A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genesMetastatic bone disease: role of transcription factors and future targets.Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancerSmall integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancerCancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motilityHoming of cancer cells to the boneRegulation of breast cancer-induced bone lesions by β-catenin protein signalingMitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.Tissue-engineered models of human tumors for cancer research.In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model.Bioengineered tumors.Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in miceMsx2 exerts bone anabolism via canonical Wnt signaling.Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cellsRunx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cellsGenetic and epigenetic regulation in nuclear microenvironments for biological control in cancerIdentification of Novel EZH2 Targets Regulating Osteogenic Differentiation in Mesenchymal Stem CellsTargeted overexpression of BSP in osteoclasts promotes bone metastasis of breast cancer cellsPathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments.Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer.Transcription-factor-mediated epigenetic control of cell fate and lineage commitment.Homeobox protein MSX2 acts as a molecular defense mechanism for preventing ossification in ligament fibroblasts.Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer.GATA4 negatively regulates bone sialoprotein expression in osteoblasts.Molecular regulation of matrix extracellular phosphoglycoprotein expression by bone morphogenetic protein-2Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancersRunx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells.The RUNX family in breast cancer: relationships with estrogen signaling.Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer.
P2860
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P2860
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells
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2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Osteoblast-related transcripti ...... metastatic breast cancer cells
@ast
Osteoblast-related transcripti ...... metastatic breast cancer cells
@en
Osteoblast-related transcripti ...... metastatic breast cancer cells
@nl
type
label
Osteoblast-related transcripti ...... metastatic breast cancer cells
@ast
Osteoblast-related transcripti ...... metastatic breast cancer cells
@en
Osteoblast-related transcripti ...... metastatic breast cancer cells
@nl
prefLabel
Osteoblast-related transcripti ...... metastatic breast cancer cells
@ast
Osteoblast-related transcripti ...... metastatic breast cancer cells
@en
Osteoblast-related transcripti ...... metastatic breast cancer cells
@nl
P2093
P3181
P1433
P1476
Osteoblast-related transcripti ...... metastatic breast cancer cells
@en
P2093
Akeila Bellahcene
Amjad Javed
Andre J Van Wijnen
Gary S Stein
George L Barnes
Jane B Lian
Kerri E Hebert
Louis C Gerstenfeld
Marian F Young
Mohammad H Kamal
P304
P3181
P407
P577
2003-05-15T00:00:00Z