Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
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The tumor suppressor PP2A Abeta regulates the RalA GTPaseA PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) proteinDephosphorylation of Carma1 by PP2A negatively regulates T-cell activationAn integrated workflow for charting the human interaction proteome: insights into the PP2A systemPP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4A landscape of driver mutations in melanomaStructure and function of the PP2A-shugoshin interactionTargeting protein serine/threonine phosphatases for drug developmentThe broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceProtein Phosphatase 2A in the Regulatory Network Underlying Biotic Stress Resistance in PlantsCounteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesPP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificitySignaling regulation of fetoplacental angiogenesisA review of ceramide analogs as potential anticancer agentsCircumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signalingCrystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor SymplekinStructural Basis of PP2A Inhibition by Small t AntigenStructural basis for regulation of protein phosphatase 1 by inhibitor-2Structural bases for recognition of Anp32/LANP proteinsStructure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau DephosphorylationCrystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase InhibitorsHelical Repeat Structure of Apoptosis Inhibitor 5 Reveals Protein-Protein Interaction ModulesStructure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylationSelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2ASeparase biosensor reveals that cohesin cleavage timing depends on phosphatase PP2A(Cdc55) regulationGeneration of active protein phosphatase 2A is coupled to holoenzyme assemblyBod1 regulates protein phosphatase 2A at mitotic kinetochoresVisualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cellsDirect and Indirect Targeting of PP2A by Conserved Bacterial Type-III Effector ProteinsThe alpha4-containing form of protein phosphatase 2A in liver and hepatic cells.The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationActivation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.The Discodermia calyx toxin calyculin a enhances cyclin D1 phosphorylation and degradation, and arrests cell cycle progression in human breast cancer cells.Alpha4 is a ubiquitin-binding protein that regulates protein serine/threonine phosphatase 2A ubiquitinationMapping of protein phosphatase-6 association with its SAPS domain regulatory subunit using a model of helical repeats.Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactionsProtein Ser/Thr phosphatases--the ugly ducklings of cell signalling.PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysis
P2860
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P2860
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@ast
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@en
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@nl
type
label
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@ast
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@en
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@nl
prefLabel
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@ast
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@en
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@nl
P356
P1433
P1476
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
@en
P2093
Uhn Soo Cho
P2888
P356
10.1038/NATURE05351
P407
P50
P577
2006-11-01T00:00:00Z
P6179
1027078509