Immunity to murine Chlamydia trachomatis genital tract reinfection involves B cells and CD4(+) T cells but not CD8(+) T cells.
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The Role of the Immune Response in Chlamydia trachomatis Infection of the Male Genital Tract: A Double-Edged SwordInfluence of the tryptophan-indole-IFNγ axis on human genital Chlamydia trachomatis infection: role of vaginal co-infectionsIntravaginal Chlamydia trachomatis Challenge Infection Elicits TH1 and TH17 Immune Responses in Mice That Promote Pathogen Clearance and Genital Tract DamageA vaccine formulated with the major outer membrane protein can protect C3H/HeN, a highly susceptible strain of mice, from a Chlamydia muridarum genital challengeChlamydial protease-like activity factor--insights into immunity and vaccine developmentProtection against Chlamydia promoted by a subunit vaccine (CTH1) compared with a primary intranasal infection in a mouse genital challenge model.CD8+ T cells define an unexpected role in live-attenuated vaccine protective immunity against Chlamydia trachomatis infection in macaquesIncreased immunoaccessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with Chlamydia muridarum.Immunization with the attenuated plasmidless Chlamydia trachomatis L2(25667R) strain provides partial protection in a murine model of female genitourinary tract infectionSimultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract.A live and inactivated Chlamydia trachomatis mouse pneumonitis strain induces the maturation of dendritic cells that are phenotypically and immunologically distinct.Steroids alone or as adjunctive therapy with doxycycline fail to improve oviduct damage in mice infected with Chlamydia muridarum.The female lower genital tract is a privileged compartment with IL-10 producing dendritic cells and poor Th1 immunity following Chlamydia trachomatis infection.Characterization of human immunodeficiency virus Gag-specific gamma interferon-expressing cells following protective mucosal immunization with alphavirus replicon particles.Chlamydia muridarum T-cell antigens formulated with the adjuvant DDA/TDB induce immunity against infection that correlates with a high frequency of gamma interferon (IFN-gamma)/tumor necrosis factor alpha and IFN-gamma/interleukin-17 double-positiveThe effect of infectious dose on humoral and cellular immune responses in Chlamydophila caviae primary ocular infectionResolution of secondary Chlamydia trachomatis genital tract infection in immune mice with depletion of both CD4+ and CD8+ T cells.Expression of genes encoding Th1 cell-activating cytokines and lymphoid homing chemokines by chlamydia-pulsed dendritic cells correlates with protective immunizing efficacy.Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein can elicit a protective immune response against a genital challengeThe protective effect of antibody in immunity to murine chlamydial genital tract reinfection is independent of immunoglobulin A.Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge.Dendritic cells pulsed with a recombinant chlamydial major outer membrane protein antigen elicit a CD4(+) type 2 rather than type 1 immune response that is not protective.Immunity to murine chlamydial genital infection.A Chlamydia trachomatis-specific Th2 clone does not provide protection against a genital infection and displays reduced trafficking to the infected genital mucosaImmunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein by use of CpG oligodeoxynucleotides as an adjuvant induces a protective immune response against an intranasal chlamydial challengeMaternal immunity partially protects newborn mice against a Chlamydia trachomatis intranasal challengeCD4+ T cells and antibody are required for optimal major outer membrane protein vaccine-induced immunity to Chlamydia muridarum genital infection.Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria.B-cell-deficient mice show an exacerbated inflammatory response in a model of Chlamydophila abortus infection.Enhancement of the protective efficacy of a Chlamydia trachomatis recombinant vaccine by combining systemic and mucosal routes for immunization.Induction of protective immunity against Chlamydia muridarum intravaginal infection with the chlamydial immunodominant antigen macrophage infectivity potentiator.Induction of immune memory by a multisubunit chlamydial vaccineTrachoma: protective and pathogenic ocular immune responses to Chlamydia trachomatis.A Vibrio cholerae ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin.Characterization of humoral immune responses to chlamydial HSP60, CPAF, and CT795 in inflammatory and severe trachoma.Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infectionVaccination against Chlamydia genital infection utilizing the murine C. muridarum model.Murine Chlamydia trachomatis genital infection is unaltered by depletion of CD4+ T cells and diminished adaptive immunity.Activation of the NLRP3 inflammasome by vault nanoparticles expressing a chlamydial epitope.Immunization with live and dead Chlamydia muridarum induces different levels of protective immunity in a murine genital tract model: correlation with MHC class II peptide presentation and multifunctional Th1 cells.
P2860
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P2860
Immunity to murine Chlamydia trachomatis genital tract reinfection involves B cells and CD4(+) T cells but not CD8(+) T cells.
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2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Immunity to murine Chlamydia t ...... ction involves B cells and CD4
@nl
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@ast
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@en
type
label
Immunity to murine Chlamydia t ...... ction involves B cells and CD4
@nl
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@ast
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@en
prefLabel
Immunity to murine Chlamydia t ...... ction involves B cells and CD4
@nl
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@ast
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@en
P2093
P2860
P1476
Immunity to murine Chlamydia t ...... cells but not CD8(+) T cells.
@en
P2093
H D Caldwell
R P Morrison
S G Morrison
P2860
P304
P356
10.1128/IAI.68.12.6979-6987.2000
P407
P577
2000-12-01T00:00:00Z