Mechanisms promoting translocations in editing and switching peripheral B cells. - Wikidata - wikimedia - TriplyDB

Mechanisms promoting translocations in editing and switching peripheral B cells.

Mechanisms promoting translocations in editing and switching peripheral B cells.

http://www.wikidata.org/entity/Q34008189

about

Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)Somatic Rearrangement in B Cells: It's (Mostly) Nuclear Physics Molecular programming of B cell memory The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex Structural basis for DNA recognition and nuclease processing by the Mre11 homologue SbcD in double-strand breaks repair B cell receptor editing in tolerance and autoimmunity Snaps and mends: DNA breaks and chromosomal translocations The response to and repair of RAG-mediated DNA double-strand breaks Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival.Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.Role of the translocation partner in protection against AID-dependent chromosomal translocations Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.Generation and repair of AID-initiated DNA lesions in B lymphocytes.ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.Origin of chromosomal translocations in lymphoid cancer.Delineating Rearrangements in Single Yeast Artificial Chromosomes by Quantitative DNA Fiber Mapping.Non-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways.Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.AID and somatic hypermutation.Mechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice.AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.AID-initiated DNA lesions are differentially processed in distinct B cell populations.APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis.The proximal J kappa germline-transcript promoter facilitates receptor editing through control of ordered recombination.SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling Genetic reporter system for oncogenic Igh-Myc translocations in mice.Enforced expression of the apoptosis inhibitor Bcl-2 ablates tolerance induction in DNA-reactive B cells through a novel mechanism Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region.Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway

P2860

Q24629508-8448557D-BCAC-40A8-B390-48703BC658A7 Q26798098-BBC67204-9056-4416-A93C-8DE89D38C214 Q26829944-FD5CD80F-C323-4EBC-B3C4-1844E4B5C863 Q27667404-A3237340-9F3D-4910-B41B-57F86D88FDA4 Q27674381-E7AC814A-D5D0-4E91-A3DE-12EFFE0B5B22 Q27689081-21E9E668-1C63-4AB3-9302-8BDE18A820DC Q27692084-CD7DA8EA-E18B-4E42-A9CB-A0B274E37F94 Q28082525-822A77C8-DA57-46CF-97E5-61E37DF21452 Q28256889-91D98F53-3A05-4FD0-A734-C71049DC23DA Q28274000-7A61DD2D-A87C-4E8B-8F40-252B4DF40908 Q28485943-99AC245A-7736-41AD-95D8-FB7F647392C0 Q30363869-86BD6396-E68E-4C25-B591-B00B2A22B845 Q33573534-13C75823-8139-4F8C-AC40-8D3ADB1D0864 Q33588393-60B69613-1ACB-4A1B-984A-3FC14D178638 Q33591714-D264E258-6180-4C22-9E14-FF3BD2316284 Q33591867-F75A927C-F396-4F6E-B9B3-BB48B2E03B0F Q33656097-3ACA3337-6732-4C1B-85AA-C0630F8ED7D0 Q33690522-3AF7F776-8598-4FAA-87A5-C990D40A45DA Q33725435-F44D96E4-D3B5-43A4-997F-E92447AE4284 Q33733981-2494A7EF-E99F-42BC-9FA9-46940A6B314B Q33794964-2C23C711-4FAC-44EC-BC55-E017EAD2E73B Q33870612-9AD2A425-2DF8-4B00-BE2F-B9B2AC9BF983 Q33870690-53EE1CE5-2399-495F-892C-1069467E814A Q33871220-6DB687B5-DABF-43B3-B704-1EB2203AAB64 Q33925876-19BB617C-CE09-414E-9F3E-4070EBD1A2F2 Q33979941-4F351DDC-919C-4AB4-A60B-B6C7D4F0361A Q34118000-769872D7-5566-47BB-96F1-C00E185B7448 Q34143276-E0CB684E-8BBE-4AF8-BEBD-97EB27A0B92F Q34328206-FC91FEBB-67F0-4318-8C24-F722989E8436 Q34550504-A8060A9E-456B-4129-B5CB-9C4CBBC9FD9F Q34661364-9E035223-E595-496C-A552-566F5C2C93A8 Q34729503-0B4F1EAD-216F-4E11-8D71-C2E6B2B1812C Q34760276-C6C0B17F-9751-481B-977C-F567FE9A2840 Q34822524-AF9E8E08-701D-4D89-A729-2098EEEE1341 Q34890876-164042E5-C9D4-45F2-A617-E415AB916AEB Q35026963-83226EE0-B58C-480A-B67F-5B3C20426B2D Q35032627-EB493A3E-908B-4CBE-B65A-BDADC7CB4957 Q35124628-52BE70B3-4B5B-4E83-A3B2-D30E6B2212D0 Q35304991-3AD606A9-1441-4B04-A30C-F4CD902F6B73 Q35311235-05B5A408-D2C0-4690-A44D-A8C9028DF636

P2860

Mechanisms promoting translocations in editing and switching peripheral B cells.

http://www.wikidata.org/entity/Q34008189

description

2009 nî lūn-bûn

@nan

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Mechanisms promoting translocations in editing and switching peripheral B cells.

@ast

Mechanisms promoting translocations in editing and switching peripheral B cells.

@en

Mechanisms promoting translocations in editing and switching peripheral B cells.

@nl

type

label

Mechanisms promoting translocations in editing and switching peripheral B cells.

@ast

Mechanisms promoting translocations in editing and switching peripheral B cells.

@en

Mechanisms promoting translocations in editing and switching peripheral B cells.

@nl

prefLabel

Mechanisms promoting translocations in editing and switching peripheral B cells.

@ast

Mechanisms promoting translocations in editing and switching peripheral B cells.

@en

Mechanisms promoting translocations in editing and switching peripheral B cells.

@nl

P1433

Q34008189-BF3FCE94-6E29-4361-9ACC-EC414B97A096

P1476

Q34008189-1BD90F3F-AD81-4FE8-93EF-7EA404DAA26D

P2093

Q34008189-0A4E21DF-BB52-4A9B-AFF7-0787DEC66B96

Q34008189-32036282-58DC-4101-B0E7-6E66154EA6A9

Q34008189-38F93AF0-161E-4335-B6F8-AB5EFF9AFDDB

Q34008189-4BDF59DC-3355-48AB-8B0C-A6885A5B4249

Q34008189-4E1E6B8E-23C2-4137-83DD-2C4D0FDFD4AD

Q34008189-740B922A-EDB9-4719-AFCC-FA25D9247533

Q34008189-827BB036-65A1-4C2C-9610-FDAEE49B9172

Q34008189-A1973CFF-C633-4A80-85E8-6E28972EB1C8

Q34008189-B8310D17-1BBC-440A-9C46-13043E581583

Q34008189-CE9D2EDE-8F4D-4B1C-8E97-B7DC401C75B4

P2860

Q34008189-05D255C9-1818-428D-9132-779FA33C95D7

Q34008189-07FA7F58-8608-488F-A4E9-8FFA8BA148FD

Q34008189-1C2D5FE3-BA6B-4583-83F9-112D2E6D188A

Q34008189-252C8ECF-6FD0-42F2-A58D-254EB99423D9

Q34008189-294ABF0E-3F7E-4EF1-8DAD-C1A0C50F40FD

Q34008189-36A32B56-19AB-4762-931F-E3C9897EEE4A

Q34008189-3DBC6337-5A57-4C66-85D7-7E4DD0D10546

Q34008189-3FD63BE7-608F-4115-A249-EB4BB8A0E849

Q34008189-42EEC2A3-1146-4FC6-9034-9DB126EC387A

Q34008189-4E3500C7-EE13-46C8-9077-963AC41F0AC2

P2888

Q34008189-72F5C0D8-DFFB-46D8-82AF-38AFDB263579

P304

Q34008189-47558C0F-F361-4411-AD54-E821769A578D

P31

Q34008189-6A24C909-8A7A-4A8A-87DA-424DDDC5858A

P356

Q34008189-502C2783-34F2-4AFB-B04D-48583182D74A

P407

Q34008189-10E36148-2931-4BAC-A21A-63D1934531B0

P433

Q34008189-5952F972-95D2-40E5-9DDD-94070A624363

P478

Q34008189-4E704985-930B-4001-AC53-B534EDD64FDF

P50

Q34008189-69A460A5-0EB1-41BB-8AD9-18EE83066B0F

P577

Q34008189-DA6F8316-73FD-4A33-A4FB-1EB8FA4F86DA

P5875

Q34008189-F53AD6CE-BD26-434F-8773-18B23D01D13B

P6179

Q34008189-148ECEE9-631C-4D83-9A45-DD5FD50201E4

P698

Q34008189-CFC8F290-6C66-45E0-9F64-849D3206BAFC

P932

Q34008189-CB114EEB-83CC-4005-8D60-FF60B4BFD038

P356

P1433

P1476

Mechanisms promoting translocations in editing and switching peripheral B cells.

@en

P2093

Ali A Zarrin

http://www.w3.org/2001/XMLSchema#string

Andre Nussenzweig

http://www.w3.org/2001/XMLSchema#string

Catherine T Yan

http://www.w3.org/2001/XMLSchema#string

Duane R Wesemann

http://www.w3.org/2001/XMLSchema#string

Erica Hansen

http://www.w3.org/2001/XMLSchema#string

Frederick W Alt

http://www.w3.org/2001/XMLSchema#string

Jing H Wang

http://www.w3.org/2001/XMLSchema#string

Monica Gostissa

http://www.w3.org/2001/XMLSchema#string

Peter Goff

http://www.w3.org/2001/XMLSchema#string

Simone Difilippantonio

http://www.w3.org/2001/XMLSchema#string

P2860

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

IgH class switching and translocations use a robust non-classical end-joining pathway

Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.

Myc dynamically and preferentially relocates to a transcription factory occupied by Igh

P2888

P304

231-236

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NATURE08159

http://www.w3.org/2001/XMLSchema#string

P407

P433

7252

http://www.w3.org/2001/XMLSchema#string

P478

460

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

232758559

http://www.w3.org/2001/XMLSchema#string

P6179

1001723874

http://www.w3.org/2001/XMLSchema#string

P698

19587764

http://www.w3.org/2001/XMLSchema#string

P932

2907259

http://www.w3.org/2001/XMLSchema#string