Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis - Wikidata - wikimedia - TriplyDB

Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis

Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis

http://www.wikidata.org/entity/Q34009826

about

Dinosaurs and ancient civilizations: reflections on the treatment of cancer The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.Induction of ΔNp63 by the newly identified keratinocyte-specific transforming growth factor β Signaling Pathway with Smad2 and IκB Kinase α in squamous cell carcinoma.Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6).Molecular Validation of PACE4 as a Target in Prostate Cancer The interconnectedness of cancer cell signaling.Expression of paired basic amino acid-cleaving enzyme 4 (PACE4) correlated with prognosis in non-small cell lung cancer (NSCLC) patients.Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays.Transgenic overexpression of the proprotein convertase furin enhances skin tumor growth Mechanism of Fine-tuning pH Sensors in Proprotein Convertases: IDENTIFICATION OF A pH-SENSING HISTIDINE PAIR IN THE PROPEPTIDE OF PROPROTEIN CONVERTASE 1/3.Opposite roles of furin and PC5A in N-cadherin processing.Proprotein convertase inhibition: Paralyzing the cell's master switches.Enhanced UV-induced skin carcinogenesis in transgenic mice overexpressing proprotein convertases.On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications.Therapeutic uses of furin and its inhibitors: a patent review.Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity.Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells.Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integration Proteomic Study to Survey the CIGB-552 Antitumor Effect Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth.Proprotein convertase subtilisin/kexin type 6 activates the extracellular signal-regulated kinase 1/2 and Wnt family member 3A pathways and promotes in vitro proliferation, migration and invasion of breast cancer MDA-MB-231 cells.

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P2860

Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis

http://www.wikidata.org/entity/Q34009826

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

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Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

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Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

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type

label

Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

@ast

Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

@en

Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

@nl

prefLabel

Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

@ast

Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

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Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

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Proprotein convertase inhibiti ...... tumorigenesis, and metastasis

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Andres J P Klein-Szanto

http://www.w3.org/2001/XMLSchema#string

Daniel E Bassi

http://www.w3.org/2001/XMLSchema#string

Edna Cukierman

http://www.w3.org/2001/XMLSchema#string

Jirong Zhang

http://www.w3.org/2001/XMLSchema#string

Jonathan Cenna

http://www.w3.org/2001/XMLSchema#string

Samuel Litwin

http://www.w3.org/2001/XMLSchema#string

P2860

Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin

Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4)

Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7

Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases

Furin at the cutting edge: from protein traffic to embryogenesis and disease

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice

Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation

The proprotein convertases

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

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516-526

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scholarly article

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10.1593/NEO.92030

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7

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12

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45282945

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20651981

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2907578

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