Null mutations in human and mouse orthologs frequently result in different phenotypes. - Wikidata - wikimedia - TriplyDB

Null mutations in human and mouse orthologs frequently result in different phenotypes.

Null mutations in human and mouse orthologs frequently result in different phenotypes.

http://www.wikidata.org/entity/Q34011529

about

Testing the ortholog conjecture with comparative functional genomic data from mammals Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes From mouse to human: evolutionary genomics analysis of human orthologs of essential genes Integrative annotation of variants from 1092 humans: application to cancer genomics The methodological quality of animal research in critical care: the public face of science Mouse genetic and phenotypic resources for human genetics DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes Defining the role of essential genes in human disease The PsychENCODE project New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation Myeloperoxidase: a front-line defender against phagocytosed microorganisms DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases A general framework for estimating the relative pathogenicity of human genetic variants A manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology.The ortholog conjecture is untestable by the current gene ontology but is supported by RNA sequencing data.Effect of duplicate genes on mouse genetic robustness: an update.Moss and liverwort xyloglucans contain galacturonic acid and are structurally distinct from the xyloglucans synthesized by hornworts and vascular plants.An evolutionary and structural characterization of mammalian protein complex organization.Why is the correlation between gene importance and gene evolutionary rate so weak?A tree shrew glioblastoma model recapitulates features of human glioblastoma The use of orthologous sequences to predict the impact of amino acid substitutions on protein function.The biological context of HIV-1 host interactions reveals subtle insights into a system hijack A yeast's eye view of mammalian reproduction: cross-species gene co-expression in meiotic prophase.Comparison of computational models for assessing conservation of gene expression across species.A simple meningococcal sepsis prognostic score: focusing on the human animal Why human disease-associated residues appear as the wild-type in other species: genome-scale structural evidence for the compensation hypothesis.Contrasting genetic paths to morphological and physiological evolution.The Mouse Lemur, a Genetic Model Organism for Primate Biology, Behavior, and Health.Biological interaction networks are conserved at the module level Gene family size conservation is a good indicator of evolutionary rates.Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information Health and population effects of rare gene knockouts in adult humans with related parents MamPhEA: a web tool for mammalian phenotype enrichment analysis.Modes of gene duplication contribute differently to genetic novelty and redundancy, but show parallels across divergent angiosperms.Molecular foundations of reproductive lethality in Arabidopsis thaliana.Predicting the lethal phenotype of the knockout mouse by integrating comprehensive genomic data Highly Specific Modulators of Protein Kinase C Localization: Applications to Heart Failure Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans.Interpretation of genomic variants using a unified biological network approach.

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P2860

Null mutations in human and mouse orthologs frequently result in different phenotypes.

http://www.wikidata.org/entity/Q34011529

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@ast

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@en

Null mutations in human and mouse orthologs frequently result in different phenotypes.

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type

label

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@ast

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@en

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@nl

prefLabel

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@ast

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@en

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@nl

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P1476

Null mutations in human and mouse orthologs frequently result in different phenotypes.

@en

P2093

Ben-Yang Liao

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Jianzhi Zhang

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P2860

Evolution at two levels: on genes and form

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

The knockout mouse project

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae

A gene atlas of the mouse and human protein-encoding transcriptomes

Developmental rescue of Drosophila cephalic defects by the human Otx genes

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

PAML 4: phylogenetic analysis by maximum likelihood

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