Leptin: a novel therapeutic strategy for Alzheimer's disease - Wikidata - wikimedia - TriplyDB

Leptin: a novel therapeutic strategy for Alzheimer's disease

Leptin: a novel therapeutic strategy for Alzheimer's disease

http://www.wikidata.org/entity/Q34015256

about

Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment The Possible Roles of the Dentate Granule Cell's Leptin and Other Ciliary Receptors in Alzheimer's Neuropathology Role of leptin resistance in the development of obesity in older patients Acute leptin treatment enhances functional recovery after spinal cord injury Hunger in the absence of caloric restriction improves cognition and attenuates Alzheimer's disease pathology in a mouse model Ionizing Radiation-Induced Immune and Inflammatory Reactions in the Brain.Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential.The therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease.Vascular risk factors: imaging and neuropathologic correlates.Adipocytokines and CD34 progenitor cells in Alzheimer's disease Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices Visceral fat is associated with lower brain volume in healthy middle-aged adults.β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway The procognitive effects of leptin in the brain and their clinical implications Plasma leptin levels are not predictive of dementia in patients with mild cognitive impairment.The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain.Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus.ZiBuPiYin recipe protects db/db mice from diabetes-associated cognitive decline through improving multiple pathological changes Serum leptin, thyroxine and thyroid-stimulating hormone levels interact to affect cognitive function among US adults: evidence from a large representative survey.Repositioning leptin as a therapy for Alzheimer's disease Alzheimer's disease: pathological mechanisms and recent insights.Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet.Alzheimer's disease promotion by obesity: induced mechanisms-molecular links and perspectives Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice.Leptin signaling and Alzheimer's disease.Fat-mass-related hormone, plasma leptin, predicts brain volumes in the elderly.Lipids and adipokines as risk factors for Alzheimer's disease.A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect Imaging the Alzheimer brain.Short duration of sleep is associated with hyperleptinemia in Taiwanese adults.Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance.An overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders.Adiponectin Receptors Are Less Sensitive to Stress in a Transgenic Mouse Model of Alzheimer's Disease.Neuroendocrinology-based therapy for Alzheimer's disease.Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer's disease.Leptin signaling plays a critical role in the geniposide-induced decrease of tau phosphorylation.Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol.Association of adiponectin, leptin and resistin with inflammatory markers and obesity in dementia.

P2860

Q24629027-98017ECE-19CB-4505-B269-F3689AB7CD26 Q24630213-61E01AC3-C761-4D5F-B0F5-5072E4F343D8 Q26799893-726E4670-229A-4A26-A26B-6AE5D06AE02F Q26799897-5F943F9F-D5DB-4CEC-A314-E35D63122474 Q26824127-E21D4884-A973-4089-8DDE-3A58864A36B8 Q27304357-0E356592-0817-4F1A-918B-230FAD5B9338 Q28485899-05D00545-369C-4707-A3D6-B052F53F62FB Q33639101-7DD36E4C-E33B-449D-B114-8A7B8106DF34 Q33692408-14478F4C-078C-4CDB-A99C-F3C045DA6C22 Q33851630-57E0DCAC-5F35-4085-A22F-ECBA499225E2 Q33905844-DD66EB25-32F2-4EFD-B677-A0137DCCE18E Q33919734-900D9E3B-4C50-4C80-8EF6-C85432EDB3DF Q34075070-D19FEF48-F9F6-4EDB-966B-88B9B2B4ACA2 Q34105185-3C7FABD9-52A9-41B4-A3AE-472845C5E209 Q34267894-6EF2BC79-4F93-465D-9278-59D15A32CF08 Q34389081-51EEC628-59C2-4570-9DAA-CE7141371EA2 Q34630992-B53B3CBD-EF53-4D5D-99E5-BB999AEBA964 Q34764030-4DB81EBE-DB74-48DF-B0D2-4486B353E39A Q35063700-F8DFD99B-078F-4F43-8E76-05A0E49931E4 Q35116204-460D3D7E-0168-4980-BD15-F165E2B2C8CE Q35511113-22945824-E4B3-4FE3-99AB-588C24D3E432 Q35569809-90553CFF-5AB5-44D0-A16B-BE6469329153 Q35687044-4BD97590-79A6-4160-8BFF-2B335F136FEA Q35976627-C0C36373-5B03-4C12-9C7E-55ACA329A99D Q36026292-8C8C3203-5C91-4828-962A-C22FCEA04685 Q36051462-6E2E2F1B-465E-4773-B8B0-624C25755120 Q36576492-DD06875F-49B8-441B-9EA7-7CA3008F9435 Q36792655-828CDA10-15B4-47F8-AC8C-5479EF91175F Q37066912-8EDBAE34-E3D0-48DE-BB40-4DC0B2D9EC06 Q37070656-47B24232-3EEE-4336-8618-0DD9BEE9DAC7 Q37141502-27DA2E79-78BB-4313-B763-E67FA0ACE811 Q37185445-D3CB8A42-D3CC-40F5-9D48-CF87FB38FF6F Q37402339-AF5A390D-B00B-4D9D-8E90-9E8DF85CECD8 Q37733587-A51EED98-025E-40DB-9A96-05CBD10A4310 Q37746842-BB240D7D-8519-41AB-B349-0323B1061FDC Q37995980-717C827A-C2B9-4ED7-9B91-18B3FB9FEE97 Q38230391-4A5FA1E2-AB23-4FEC-9E6D-3B24E7F20E0A Q38950350-98ECE02F-2C68-4DC3-84B3-6549562C2984 Q39461274-CAF91A38-333A-487C-8304-17C0F509DC99 Q41039610-943C2432-211B-417C-B332-A10E7824893D

P2860

Leptin: a novel therapeutic strategy for Alzheimer's disease

http://www.wikidata.org/entity/Q34015256

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Leptin: a novel therapeutic strategy for Alzheimer's disease

@ast

Leptin: a novel therapeutic strategy for Alzheimer's disease

@en

Leptin: a novel therapeutic strategy for Alzheimer's disease

@nl

type

label

Leptin: a novel therapeutic strategy for Alzheimer's disease

@ast

Leptin: a novel therapeutic strategy for Alzheimer's disease

@en

Leptin: a novel therapeutic strategy for Alzheimer's disease

@nl

prefLabel

Leptin: a novel therapeutic strategy for Alzheimer's disease

@ast

Leptin: a novel therapeutic strategy for Alzheimer's disease

@en

Leptin: a novel therapeutic strategy for Alzheimer's disease

@nl

P1433

Q34015256-CF0A9A29-8327-443A-99BA-55A286114F5E

P1476

Q34015256-BE76CBA1-82DF-4FA7-B947-F9ECA2A01AB9

P2093

Q34015256-09D6BD82-389E-4D54-B5D5-50CB82C06201

Q34015256-20C58372-6C68-4073-88F0-327B34D5996F

Q34015256-321D7600-6982-4340-ABF8-BA726CF37363

Q34015256-46FECEFE-A224-45B7-85A3-FB06D742DB6F

Q34015256-6C9500E2-C89F-4D69-866F-44821480DCC8

Q34015256-A767483A-071D-4154-BFC8-22382A460E1E

Q34015256-AB2E139B-FA59-493F-9575-C3CA6BE8D4CD

Q34015256-EB3A8523-527D-4221-95AF-651C501A4C20

P2860

Q34015256-01312803-7FF0-45DC-A630-F7C687AA993A

Q34015256-01D8A310-B0E0-4B3A-86AC-91596B7B85C9

Q34015256-0284B353-2090-4A76-88C4-4F60A2E370B3

Q34015256-02E02832-922E-48DA-A5FB-56E139E4AFE7

Q34015256-0A55E8C5-DC45-436C-BF92-7E63185B2482

Q34015256-1150AC43-91B0-493F-8AB7-E396D71229E5

Q34015256-1BDA1044-FCB9-485A-9027-12D75E42ABB2

Q34015256-1FD3002A-E7F3-459F-8FE3-986E906875CC

Q34015256-227E7DEA-551C-477D-BEDA-B26ABC809699

Q34015256-2587111F-CD2A-49F6-A323-6EFF123F5976

P304

Q34015256-3CD8F684-B662-4ECB-9806-5B9DD67295AF

P31

Q34015256-2B0A482F-B7C1-4C47-9F20-53E6428ACC2D

P356

Q34015256-45D16C76-0F40-49FF-B8BE-C7C87C4FCF6C

P433

Q34015256-DB4BD823-5434-4D83-A9DF-D4D8BC5CB496

P478

Q34015256-FE7D8529-B941-4483-9F86-5231F373164C

P50

Q34015256-90927B03-7A00-4571-B913-CB5C8E32F738

Q34015256-AB35C95A-E955-4968-ACD3-7233FB74701F

Q34015256-E1073A09-27D2-498F-8D9E-E08D677D0360

P577

Q34015256-890E1D31-A823-483F-A772-B65D9379D761

P698

Q34015256-132651BD-BE53-4660-A16D-8F28E76BB57A

P921

Q34015256-378FB1F2-86FB-4F66-B2FD-34A6B7433925

P932

Q34015256-A297339B-47A5-4A8F-A642-29C2AF093A55

P356

P1433

Journal of Alzheimer's Disease

P1476

Leptin: a novel therapeutic strategy for Alzheimer's disease

@en

P2093

Benjamin Wolozin

http://www.w3.org/2001/XMLSchema#string

Gemma Casadesus

http://www.w3.org/2001/XMLSchema#string

J Wesson Ashford

http://www.w3.org/2001/XMLSchema#string

Jane M Johnston

http://www.w3.org/2001/XMLSchema#string

Nikolaos K Robakis

http://www.w3.org/2001/XMLSchema#string

Nikolaos Tezapsidis

http://www.w3.org/2001/XMLSchema#string

Sraboni Sarkar

http://www.w3.org/2001/XMLSchema#string

Steven J Greco

http://www.w3.org/2001/XMLSchema#string

P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Positional cloning of the mouse obese gene and its human homologue

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

Crystal structure of the obese protein leptin-E100

Alzheimer's disease: the cholesterol connection

P304

731-740

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.3233/JAD-2009-1021

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

Mark Anthony Smith

P577

2009-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19387109

http://www.w3.org/2001/XMLSchema#string

P921

Alzheimer's disease

P932

2908903

http://www.w3.org/2001/XMLSchema#string