Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
about
Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteinsAnthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune responseToxin-based therapeutic approachesPhotoacoustic Imaging for Cancer Detection and StagingIn vivo, noninvasive, label-free detection and eradication of circulating metastatic melanoma cells using two-color photoacoustic flow cytometry with a diode laserChemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor.Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.Cationic polyamines inhibit anthrax lethal factor proteasePerturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma.Pseudomonas aeruginosa exotoxin A reduces chemoresistance of oral squamous carcinoma cell via inhibition of heat shock proteins 70 (HSP70).Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections.Anti-proliferative role of recombinant lethal toxin of Bacillus anthracis on primary mammary ductal carcinoma cells revealing its therapeutic potential.Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae.MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.Heterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxin.Channel-forming bacterial toxins in biosensing and macromolecule deliveryDysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunitiesBroad expression analysis of human ANTXR1/TEM8 transcripts reveals differential expression and novel splizce variantsPotent antitumor activity of a urokinase-activated engineered anthrax toxin.Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapyMolecular determinants for a cardiovascular collapse in anthraxPharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate.Raf-1 activation prevents caspase 9 processing downstream of apoptosome formation.Anthrax lethal factor represses glucocorticoid and progesterone receptor activity.Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.Anthrax toxin: structures, functions and tumour targeting.Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cellsPhospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF).Cytotoxicity of anthrax lethal toxin to human acute myeloid leukemia cells is nonapoptotic and dependent on extracellular signal-regulated kinase 1/2 activity.Induction of Apoptosis by PQ1, a Gap Junction Enhancer that Upregulates Connexin 43 and Activates the MAPK Signaling Pathway in Mammary Carcinoma CellsMatrix metalloproteinase-activated anthrax lethal toxin demonstrates high potency in targeting tumor vasculatureOncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions.Regulation of Apoptosis by Gram-Positive Bacteria: Mechanistic Diversity and Consequences for Immunity.Recent discoveries in the genetics of melanoma and their therapeutic implications.Targeting the RAS pathway in melanoma.Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma.Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.A new era: melanoma genetics and therapeutics.Extracellular metalloproteases from bacteria.
P2860
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P2860
Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@ast
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@en
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@nl
type
label
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@ast
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@en
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@nl
prefLabel
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@ast
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@en
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@nl
P2093
P2860
P50
P356
P1476
Apoptosis and melanogenesis in ...... ctivated protein kinase kinase
@en
P2093
George F Vande Woude
Han-Mo Koo
Matt VanBrocklin
P2860
P304
P356
10.1073/PNAS.052707699
P407
P577
2002-02-26T00:00:00Z