Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration.
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Drusen complement components C3a and C5a promote choroidal neovascularizationSusceptibility genes for age-related maculopathy on chromosome 10q26.Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degenerationThe expression of advanced glycation endproduct receptors in rpe cells associated with basal deposits in human maculasStructural basis for engagement by complement factor H of C3b on a self surfaceCFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degenerationExtended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implicationsA variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degenerationCFH Y402H confers similar risk of soft drusen and both forms of advanced AMDThe genetics of schizophreniaAMD Genetics in India: The Missing LinksGenetics of immunological and inflammatory components in age-related macular degenerationToday and future of age-related macular degenerationAnimal models of age related macular degenerationStructure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphismA common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degenerationDisease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structureGenetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysisUsing current data to define new approach in age related macular degeneration: need to accelerate translational research.Efficient study designs for test of genetic association using sibship data and unrelated cases and controls.Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.Age-related macular degeneration: a perspective on genetic studies.Genetic markers and biomarkers for age-related macular degeneration.Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction.Haplotypes in the complement factor H (CFH) gene: associations with drusen and advanced age-related macular degeneration.Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes.The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degenerationAnalysis of the indel at the ARMS2 3'UTR in age-related macular degeneration.Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration.Genetic loci that control the size of laser-induced choroidal neovascularizationThe Minnesota Grading System using fundus autofluorescence of eye bank eyes: a correlation to age-related macular degeneration (an AOS thesis).rs5888 variant of SCARB1 gene is a possible susceptibility factor for age-related macular degeneration.Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degenerationAn association study of SERPING1 gene and age-related macular degeneration in a Han Chinese populationGenetic risk, ethnic variations and pharmacogenetic biomarkers in age-related macular degeneration and polypoidal choroidal vasculopathyGenome-wide association studies: progress and potential for drug discovery and development.An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism.Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics.The retinal pigment epithelium in health and disease
P2860
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P2860
Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Strong association of the Y402 ...... -related macular degeneration.
@ast
Strong association of the Y402 ...... -related macular degeneration.
@en
Strong association of the Y402 ...... -related macular degeneration.
@en-gb
Strong association of the Y402 ...... -related macular degeneration.
@nl
type
label
Strong association of the Y402 ...... -related macular degeneration.
@ast
Strong association of the Y402 ...... -related macular degeneration.
@en
Strong association of the Y402 ...... -related macular degeneration.
@en-gb
Strong association of the Y402 ...... -related macular degeneration.
@nl
prefLabel
Strong association of the Y402 ...... -related macular degeneration.
@ast
Strong association of the Y402 ...... -related macular degeneration.
@en
Strong association of the Y402 ...... -related macular degeneration.
@en-gb
Strong association of the Y402 ...... -related macular degeneration.
@nl
P2093
P2860
P356
P1476
Strong association of the Y402 ...... -related macular degeneration.
@en
P2093
Josephine Hoh
Kari E H Branham
Mingyao Li
Robert J Klein
Sapna Shah
Sepideh Zareparsi
P2860
P304
P356
10.1086/431426
P407
P577
2005-05-13T00:00:00Z