Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. - Wikidata - wikimedia - TriplyDB

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

http://www.wikidata.org/entity/Q34023042

about

Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.DNA dynamics during early double-strand break processing revealed by non-intrusive imaging of living cells Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair End-resection at DNA double-strand breaks in the three domains of life Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex.Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?Replication stress in Mammalian cells and its consequences for mitosis Genetic instability in budding and fission yeast-sources and mechanisms The role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and myths Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.Nonhomologous end joining: a good solution for bad ends CtIP-mediated resection is essential for viability and can operate independently of BRCA1.Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin End resection at double-strand breaks: mechanism and regulation.Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.A role for nuclear envelope-bridging complexes in homology-directed repair.A stochastic model of DNA fragments rejoining The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1.Fission yeast RecQ helicase Rqh1 is required for the maintenance of circular chromosomes.The role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line.Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nuclease Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair.Modeling damage complexity-dependent non-homologous end-joining repair pathway.The Ctf18RFC clamp loader is essential for telomere stability in telomerase-negative and mre11 mutant alleles.RPA antagonizes microhomology-mediated repair of DNA double-strand breaks.Fission yeast Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2.Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair.Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants 14-3-3 proteins restrain the Exo1 nuclease to prevent overresection.Ku stabilizes replication forks in the absence of Brc1.Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection Critical Function of γH2A in S-Phase Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres.CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection.Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand break repair Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining A new method to efficiently induce a site-specific double-strand break in the fission yeast Schizosaccharomyces pombe.

P2860

Q27310232-262A2AB6-C29C-45B0-9EB3-3885D7B2AA37 Q27316712-50A02F86-B19B-4B23-A05B-8B3C8257A94E Q27674627-77D8FBBB-35A2-4213-8C9A-62F96971B0C8 Q27694756-1E07E9AB-0E34-404D-86CB-8983CE760C0D Q27930908-F69CE889-0648-46BF-AB82-3880A7B997E8 Q28000088-CEC4AA96-47C4-43D8-89D9-9F931F8A7168 Q28083182-187F372E-AD89-45CB-9ACD-71FE652D1052 Q28087011-BF18FBE1-33AE-423F-AEDC-177B1A8E4CBC Q28264035-5F9F8587-AF34-4E46-9FAF-E6911A1B9254 Q28829819-479E36D5-BA53-40E0-9E91-AAC1BB11F15D Q29346873-FEC15BA5-D1EE-4B42-9014-2CA847BD9DB8 Q33625010-6E552D3B-E564-4EDF-9355-5D669093608F Q33703015-9B73CA8E-8BDA-4B4E-913C-BAB455936D48 Q33779587-E2345827-BE36-4CA8-AC71-4842862E0FC2 Q33938581-1F24F9FF-7523-43FA-8B36-2C13F5976BE6 Q33983255-75C6D725-E657-48ED-9B53-FE83A563BDAA Q34081445-2294B93B-AE82-4B62-9B8E-11007A056923 Q34427007-EEE76540-47F5-4B64-B3B1-C2529A7BC5AA Q34487643-05AFE996-B7C6-4EE5-965E-01183292DA66 Q34538921-C1E70994-93B7-487C-A887-BA4398E9AB36 Q34649915-8F4D53D1-CFCF-4A18-B0CD-5EDCEFA12BC4 Q34650076-7561123C-D8A7-4381-9E85-AB07A14E45BB Q34708378-4195430C-496A-4AF6-AB66-1B7E54DDCA6D Q35054726-407A62BB-9AA7-4D59-852E-5EB23FD27897 Q35092577-81CEC94C-DAB4-41AE-A43B-F9C0BA6CBB01 Q35095480-F9CEDCF2-A52A-478E-B08C-44F2AA0E3B03 Q35114605-A2CC9A9F-3E19-450A-AC23-4E4B3665654C Q35244543-BC9D33B9-1B24-4ECC-B406-D0C0F046B4BD Q35466760-A43D501A-4A92-4AE1-995B-B80E29BDB8AE Q35539921-59850EB7-F9CB-4CF9-9E73-53E3DB106FBE Q35583065-ECBE097C-EC5A-48E4-BB89-44843A3DDE62 Q35583181-A54B0209-841A-4757-9459-BC39A3089BEE Q35627965-2EF88A28-AE3B-4EE0-BC9F-8D21052915D9 Q35661472-B4CF947E-D6AA-490A-A5B0-DFFCE13EDC4C Q35774171-46D4B0B9-36DC-4A5E-8C42-9DA68E714C5D Q35806349-84F6CE93-635C-4F6B-A2E0-76BF02422B6E Q35995271-2B2C6F54-F1D5-4161-926D-171B36E3E0B6 Q36002411-981CC5CD-1168-4187-82DF-2EA523DDC116 Q36003205-0D6EC78D-5ACF-43C1-B9E5-50F3CFE0DC94 Q36075811-A99EBAC8-866F-4DB5-8E1C-F63844E753B9

P2860

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

http://www.wikidata.org/entity/Q34023042

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@ast

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@en

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@nl

type

label

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@ast

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@en

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@nl

prefLabel

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@ast

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@en

Release of Ku and MRN from DNA ...... epair of double-strand breaks.

@nl

P1433

Q34023042-D23D1189-A51E-4E05-856F-D6C5F255E7DF

P1476

Q34023042-0640F6E0-CED7-407E-83AB-4392E3281209

P2093

Q34023042-002D0509-838B-46C9-89BB-C5222E038138

Q34023042-0885787E-23C3-4EF2-BDC3-0E5028BE6197

P2860

Q34023042-00A6EB82-8123-4D8A-A9C5-A3279FA4374F

Q34023042-00CBEE64-588F-4717-B273-2D5CCBA3DB45

Q34023042-03D8D0DF-FC12-4D46-9363-E628565D71D2

Q34023042-061C0C53-C737-4972-9180-42771157A556

Q34023042-0783EB88-2724-4D9D-AA3A-0A4563E638B5

Q34023042-0A15FD8E-E28E-42DD-A72E-1E2F3E834783

Q34023042-0E3B0B85-9F3E-4ACF-B964-8645428BC684

Q34023042-0F27C1E8-7871-41B7-9F91-34AD1D0F8913

Q34023042-100E1E35-7268-4284-A5FF-6FD058725D21

Q34023042-111B171F-DFAA-44EA-84DF-3DD071265F4C

P304

Q34023042-686B7799-145D-4A0B-AA64-F8A047E5C1B6

P31

Q34023042-59E829F3-F346-4EF0-8AF8-979675CCAB40

P356

Q34023042-02917797-27F9-40B8-AD37-FDC00E80964E

P433

Q34023042-92F341FB-9C4F-4FBA-B124-CCF3796C4821

P478

Q34023042-7A8E9BFE-49D6-4271-926E-A746A7F54C16

P50

Q34023042-22D6A034-570F-4B61-92E6-922B69455C98

Q34023042-B7F152DD-15B1-44F8-9E1F-05E137A15592

P577

Q34023042-7F833CB1-7FFA-492C-A8BC-F6788369BCF8

P5875

Q34023042-96F4829A-A54A-484C-811B-AFD14505DF7B

P698

Q34023042-B849BCC0-7FA4-4D3A-9003-6436E2C38B26

P932

Q34023042-7B86CD5E-FD53-439F-9296-A13E6969575B

P356

JOURNAL.PGEN.1002271

P1433

P1476

Release of Ku and MRN from DNA ...... repair of double-strand breaks

@en

P2093

Paul Russell

http://www.w3.org/2001/XMLSchema#string

Petra Langerak

http://www.w3.org/2001/XMLSchema#string

P2860

DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae

Human CtIP promotes DNA end resection

DNA end resection: many nucleases make light work

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.

A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2.

Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex.

Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.

P304

e1002271

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PGEN.1002271

http://www.w3.org/2001/XMLSchema#string

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P50

Eva Mejía-Ramírez

P577

2011-09-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51652862

http://www.w3.org/2001/XMLSchema#string

P698

21931565

http://www.w3.org/2001/XMLSchema#string

P932

3169521

http://www.w3.org/2001/XMLSchema#string