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Poisoning of mitochondrial topoisomerase I by lamellarin D

Poisoning of mitochondrial topoisomerase I by lamellarin D

http://www.wikidata.org/entity/Q34024641

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Synthetic approaches to the lamellarins--a comprehensive review Alkaloids from marine invertebrates as important leads for anticancer drugs discovery and development Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity Anticancer properties of lamellarins.Natural Compounds as Anticancer Agents Targeting DNA Topoisomerases.topIb, a phylogenetic hallmark gene of Thaumarchaeota encodes a functional eukaryote-like topoisomerase IB.Gold-silver catalyzed straightforward one pot synthesis of pyrano[3,4-b]pyrrol-7(1H)-ones.Ascidian Toxins with Potential for Drug Development.

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P2860

Poisoning of mitochondrial topoisomerase I by lamellarin D

http://www.wikidata.org/entity/Q34024641

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Poisoning of mitochondrial topoisomerase I by lamellarin D

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Molecular Pharmacology

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Poisoning of mitochondrial topoisomerase I by lamellarin D

@en

P2093

Hongliang Zhang

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Katherine Fesen

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Keir C Neuman

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Keli Agama

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Salim Khiati

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Surbhi Agrawal

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Yeonee Seol

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P2860

Dual localization of human DNA topoisomerase IIIalpha to mitochondria and nucleus

Mitochondrial genetics

Drugging topoisomerases: lessons and challenges

A model for the mechanism of human topoisomerase I

DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number.

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

mtDNA mutations increase tumorigenicity in prostate cancer.

Targeting mitochondrial DNA with a platinum-based anticancer agent.

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193-199

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2

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86

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Ilaria Dalla Rosa

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2014-06-02T00:00:00Z

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