Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms. - Wikidata - wikimedia - TriplyDB

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.

http://www.wikidata.org/entity/Q34025149

about

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter Lipid nanoparticles for targeted siRNA delivery - going from bench to bedside Synthetic biology in mammalian cells: next generation research tools and therapeutics Efficient hepatic delivery of drugs: novel strategies and their significance miRNA-based therapies: strategies and delivery platforms for oligonucleotide and non-oligonucleotide agents Delivery of oligonucleotides with lipid nanoparticles Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown.Knocking down disease: a progress report on siRNA therapeutics Progress toward in vivo use of siRNAs-II MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling Morphology, structure and function characterization of PEI modified magnetic nanoparticles gene delivery system Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Docking Study.Antisense oligonucleotide therapies: the promise and the challenges from a toxicologic pathologist's perspective.Delivery is key: lessons learnt from developing splice-switching antisense therapies Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA RNAi-mediated silencing of hepatic Alas1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice High-density lipoproteins for the systemic delivery of short interfering RNA.Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide.The roles of individual mammalian argonautes in RNA interference in vivo.An amino acid-based amphoteric liposomal delivery system for systemic administration of siRNA.Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections.Next generation delivery system for proteins and genes of therapeutic purpose: why and how?A status report on RNAi therapeutics.Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo.In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight Loss of α-catenin elicits a cholestatic response and impairs liver regeneration.From phage display to nanoparticle delivery: functionalizing liposomes with multivalent peptides improves targeting to a cancer biomarker Preparation of novel curdlan nanoparticles for intracellular siRNA delivery.The effects of lipoplex formulation variables on the protein corona and comparisons with in vitro transfection efficiency Formulated minimal-length synthetic small hairpin RNAs are potent inhibitors of hepatitis C virus in mice with humanized livers.High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.Delivery of siRNA to the mouse lung via a functionalized lipopolyamine.Identification of siRNA delivery enhancers by a chemical library screen.Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.Optimized in vivo transfer of small interfering RNA targeting dermal tissue using in vivo surface electroporation.An RNA alternative to human transferrin: a new tool for targeting human cells.The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA.In vitro-in vivo translation of lipid nanoparticles for hepatocellular siRNA delivery.

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P2860

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.

http://www.wikidata.org/entity/Q34025149

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

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Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@en

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@nl

type

label

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@ast

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@en

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@nl

prefLabel

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@ast

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@en

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@nl

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P1433

Molecular Therapy

P1476

Targeted delivery of RNAi ther ...... enous ligand-based mechanisms.

@en

P2093

Akin Akinc

http://www.w3.org/2001/XMLSchema#string

Andrew Sprague

http://www.w3.org/2001/XMLSchema#string

Antonin de Fougerolles

http://www.w3.org/2001/XMLSchema#string

Dinah W Y Sah

http://www.w3.org/2001/XMLSchema#string

Eugenio Fava

http://www.w3.org/2001/XMLSchema#string

J Robert Dorkin

http://www.w3.org/2001/XMLSchema#string

James S Butler

http://www.w3.org/2001/XMLSchema#string

June Qin

http://www.w3.org/2001/XMLSchema#string

K Narayanannair Jayaprakash

http://www.w3.org/2001/XMLSchema#string

Kallanthottathil G Rajeev

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P2860

The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit

Effects of apolipoproteins A-IV and A-I on the uptake of phospholipid liposomes by hepatocytes

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.

Lipid-like materials for low-dose, in vivo gene silencing

P304

1357-1364

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scholarly article

P356

10.1038/MT.2010.85

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P433

7

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P478

18

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P50

Victor Koteliansky

P577

2010-05-11T00:00:00Z

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44590772

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20461061

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2911264

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