High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.
about
Identification of siRNA delivery enhancers by a chemical library screen.Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs.Retro-1 Analogues Differentially Affect Oligonucleotide Delivery and Toxin Trafficking.The delivery of therapeutic oligonucleotidesAnnexin A2 facilitates endocytic trafficking of antisense oligonucleotides.Cellular uptake and intracellular trafficking of oligonucleotidesChallenges in carrier-mediated intracellular delivery: moving beyond endosomal barriers.6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells.Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-mediated Silencing in Mammalian CellsIn vitro and ex vivo strategies for intracellular delivery.Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotidesRole of autophagy in cell-penetrating peptide transfection model.Therapeutic targeting of non-coding RNAs in cancer.Antisense oligonucleotides: the next frontier for treatment of neurological disorders.A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides.Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis.Structure-activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides.Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs.COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
P2860
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P2860
High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
name
High-throughput screening iden ...... l effects of oligonucleotides.
@ast
High-throughput screening iden ...... l effects of oligonucleotides.
@en
type
label
High-throughput screening iden ...... l effects of oligonucleotides.
@ast
High-throughput screening iden ...... l effects of oligonucleotides.
@en
prefLabel
High-throughput screening iden ...... l effects of oligonucleotides.
@ast
High-throughput screening iden ...... l effects of oligonucleotides.
@en
P2093
P2860
P356
P1476
High-throughput screening iden ...... l effects of oligonucleotides.
@en
P2093
E A Hull-Ryde
M A Porter
R L Juliano
W P Janzen
P2860
P304
P356
10.1093/NAR/GKV060
P407
P577
2015-02-06T00:00:00Z