GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.
about
Regulation of Aicda expression and AID activityEtoposide induces nuclear re-localisation of AIDActivation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution.AID targeting is dependent on RNA polymerase II pausing.AID/APOBEC deaminases and cancerAPOBEC3B and AID have similar nuclear import mechanisms.AID and Apobec3G haphazard deamination and mutational diversityGANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivityRegulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Lysine residue at position 22 of the AID protein regulates its class switch activity.Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.Complex regulation and function of activation-induced cytidine deaminase.Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons.Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.Activation-induced cytidine deaminase (AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich (SR) protein SRSF1Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications.A role for the RNA pol II-associated PAF complex in AID-induced immune diversificationActivation-induced Cytidine Deaminase in B Cell Immunity and Cancers.GANP protein encoded on human chromosome 21/mouse chromosome 10 is associated with resistance to mammary tumor development.GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.Defining chromosomal translocation risks in cancer.Molecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells.The role of activation-induced deaminase in antibody diversification and genomic instability.Selective cell death of p53-insufficient cancer cells is induced by knockdown of the mRNA export molecule GANP.Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites.AID Biology: A pathological and clinical perspective.Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.MCM3AP and POMP Mutations Cause a DNA-Repair and DNA-Damage-Signaling Defect in an Immunodeficient Child.Epigenomic Modifications Mediating Antibody Maturation.
P2860
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P2860
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@ast
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@en
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@nl
type
label
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@ast
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@en
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@nl
prefLabel
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@ast
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@en
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@nl
P2093
P2860
P356
P1476
GANP-mediated recruitment of a ...... oglobulin variable region DNA.
@en
P2093
Kazufumi Eda
Kazuhiko Maeda
Masahiro Kitabatake
Myron F Goodman
Nobuo Sakaguchi
Phuong Pham
Shailendra Kumar Singh
P2860
P304
23945-23953
P356
10.1074/JBC.M110.131441
P407
P577
2010-05-27T00:00:00Z