An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo.

An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo.

Item
http://www.wikidata.org/entity/Q34028492
Structural basis for catalysis at the membrane-water interface.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms.Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells.Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents.Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasisMutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites.Posttranslational Modifications of RAS Proteins.Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting.Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT.ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins
P2860

An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo.

Item
http://www.wikidata.org/entity/Q34028492
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@ast
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@en
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@nl
type
label
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@ast
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@en
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@nl
prefLabel
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@ast
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@en
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
An improved isoprenylcysteine ...... tenuates tumor growth in vivo.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932