EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells
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A kinase-independent role for EGF receptor in autophagy initiationEGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistanceResistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?Atg7 in development and disease: panacea or Pandora's Box?Chloroquine and hydroxychloroquine for cancer therapyAutophagy in cellular metabolism and cancerAutophagy modulation as a potential therapeutic target for diverse diseasesAutophagy inhibition enhances daunorubicin-induced apoptosis in K562 cellsKIT (CD117) expression in a subset of non-small cell lung carcinoma (NSCLC) patientsInduction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancerAutophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer.Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenibAn improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo.Inhibitory effect of β-elemene on human breast cancer cells.Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer.Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib.YY1-MIR372-SQSTM1 regulatory axis in autophagyLovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinibAutophagic protein Beclin 1 serves as an independent positive prognostic biomarker for non-small cell lung cancerProteasome inhibitors activate autophagy involving inhibition of PI3K-Akt-mTOR pathway as an anti-oxidation defense in human RPE cellsChloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells.Autophagosome-mediated EGFR down-regulation induced by the CK2 inhibitor enhances the efficacy of EGFR-TKI on EGFR-mutant lung cancer cells with resistance by T790M.Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancersCurcumin: updated molecular mechanisms and intervention targets in human lung cancer.Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways.Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacyEGFR tyrosine kinase inhibition induces autophagy in cancer cells.Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines.Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell linesNovel Mechanisms for the Antifibrotic Action of Nintedanib.Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells.Deconvoluting the context-dependent role for autophagy in cancerAutophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment.Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance.Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastomaInteraction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation.Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitorsBystander autophagy mediated by radiation-induced exosomal miR-7-5p in non-targeted human bronchial epithelial cellsThe anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer
P2860
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P2860
EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@ast
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@en
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@nl
type
label
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@ast
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@en
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@nl
prefLabel
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@ast
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@en
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@nl
P2093
P2860
P3181
P1433
P1476
EGFR tyrosine kinase inhibitor ...... nse in human lung cancer cells
@en
P2093
Hongming Pan
Lifeng Feng
Weidong Han
Weiting Ge
Xiaojia Wang
Xiaoying Lin
Yanshan Wang
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0018691
P407
P577
2011-01-01T00:00:00Z