Mechanistic investigation of the inhibition of Abeta42 assembly and neurotoxicity by Abeta42 C-terminal fragments
about
Modulating self-assembly of amyloidogenic proteins as a therapeutic approach for neurodegenerative diseases: strategies and mechanismsAmyloid β-Protein Assembly: The Effect of Molecular Tweezers CLR01 and CLR03Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid ProteinsModulation of Amyloid β-Protein (Aβ) Assembly by Homologous C-Terminal Fragments as a Strategy for Inhibiting Aβ Toxicity.Tissue transglutaminase-mediated glutamine deamidation of beta-amyloid peptide increases peptide solubility, whereas enzymatic cross-linking and peptide fragmentation may serve as molecular triggers for rapid peptide aggregationImpact of sequence on the molecular assembly of short amyloid peptides.Structural basis for Aβ1–42 toxicity inhibition by Aβ C-terminal fragments: discrete molecular dynamics study.Short Peptides as Inhibitors of Amyloid AggregationAβ(39-42) modulates Aβ oligomerization but not fibril formationMechanism of C-Terminal Fragments of Amyloid β-Protein as Aβ Inhibitors: Do C-Terminal Interactions Play a Key Role in Their Inhibitory Activity?Discrete molecular dynamics study of oligomer formation by N-terminally truncated amyloid β-protein.Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42.Capping of aβ42 oligomers by small molecule inhibitors.A two-step strategy for structure-activity relationship studies of N-methylated aβ42 C-terminal fragments as aβ42 toxicity inhibitorsBinding of fullerenes to amyloid beta fibrils: size matters.Maintenance of amyloid β peptide homeostasis by artificial chaperones based on mixed-shell polymeric micelles.
P2860
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P2860
Mechanistic investigation of the inhibition of Abeta42 assembly and neurotoxicity by Abeta42 C-terminal fragments
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@ast
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@en
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@nl
type
label
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@ast
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@en
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@nl
prefLabel
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@ast
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@en
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@nl
P2093
P2860
P356
P1433
P1476
Mechanistic investigation of t ...... y Abeta42 C-terminal fragments
@en
P2093
Aleksey Lomakin
Bernhard H Monien
Cui-Wei Xie
Erica A Fradinger
George B Benedek
Huiyuan Li
Reeve Zemel
Sean M Spring
P2860
P304
P356
10.1021/BI100773G
P407
P577
2010-08-01T00:00:00Z