C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42.
about
Modulating self-assembly of amyloidogenic proteins as a therapeutic approach for neurodegenerative diseases: strategies and mechanismsModulation of Amyloid β-Protein (Aβ) Assembly by Homologous C-Terminal Fragments as a Strategy for Inhibiting Aβ Toxicity.Alzheimer's protective A2T mutation changes the conformational landscape of the Aβ₁₋₄₂ monomer differently than does the A2V mutation.Aβ(39-42) modulates Aβ oligomerization but not fibril formationMechanism of C-Terminal Fragments of Amyloid β-Protein as Aβ Inhibitors: Do C-Terminal Interactions Play a Key Role in Their Inhibitory Activity?Modulation in the conformational and stability attributes of the Alzheimer's disease associated amyloid-beta mutants and their favorable stabilization by curcumin: molecular dynamics simulation analysis.Identification of the primary peptide contaminant that inhibits fibrillation and toxicity in synthetic amyloid-β42.Capping of aβ42 oligomers by small molecule inhibitors.
P2860
Q28259424-5551B187-F018-4D33-B182-99930718CCA1Q33745468-8B6CEF6C-6C0B-4CB3-8321-8DDAF696E3C6Q35050571-09A1A85A-E987-421F-BFE1-42616B3329F6Q35734201-0AD98181-2C98-4AD7-B1A2-D2E47322067CQ36649779-10C0C255-EB9C-435D-B180-D72D970BA2FFQ38374439-F7BCE5A0-1DF9-45ED-98F7-7976DC208D2CQ41326548-FA29464D-405A-47CC-A6AD-E9E0679E1DCFQ41954365-76E15ABA-0507-4F94-98AA-9F60501E8E00
P2860
C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@en
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@nl
type
label
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@en
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@nl
prefLabel
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@en
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@nl
P2093
P2860
P356
P1476
C-terminal tetrapeptides inhib ...... ion at the N-terminus of Aβ42.
@en
P2093
Chunyu Wang
Dahabada H J Lopes
Erica A Fradinger
Huiyuan Li
Zhenming Du
P2860
P304
P356
10.1021/JM200982P
P407
P577
2011-11-28T00:00:00Z