Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
about
P1343
Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalkSox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cellsHDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencingTargeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signalingA genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancerA protein knockdown strategy to study the function of beta-catenin in tumorigenesisRepurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposisInteraction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition.Novel association of APC with intermediate filaments identified using a new versatile APC antibodyTopoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of Snail in tumor cells.Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells.G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway.GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer.Expression of Wnt-5a and β-catenin in primary hepatocellular carcinoma.An unusual function of RON receptor tyrosine kinase as a transcriptional regulator in cooperation with EGFR in human cancer cells.OGA heterozygosity suppresses intestinal tumorigenesis in Apc(min/+) mice.Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activation.Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinomaActivating mutations in β-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancerThe ins and outs of APC and beta-catenin nuclear transport.Colorectal pretumor progression before and after loss of DNA mismatch repairMaintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling.Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression.A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.Impact of mutant β-catenin on ABCB1 expression and therapy response in colon cancer cellsAcquisition of anoikis resistance promotes the emergence of oncogenic K-ras mutations in colorectal cancer cells and stimulates their tumorigenicity in vivo.Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin.Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancerThe canonical Wnt signalling pathway and its APC partner in colon cancer development.Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery.Small-molecule modulators of Hh and Wnt signaling pathways.Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin SignalingFusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesinDrugging the cancer stem cell compartment: lessons learned from the hedgehog and Wnt signal transduction pathwaysβ-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths.Interaction between Ku80 protein and a widely used antibody to adenomatous polyposis coli.
P2860
Q24294545-F4F13F41-A899-49A9-88A2-3C7362B26E8EQ24316490-8E112FE4-C827-4B27-B47F-DF1916ADC29FQ24319786-1401960E-EB20-47D9-B6CC-48A086663DF2Q24632740-87BEC24A-A404-4415-9D66-083B935ECD2AQ24644948-34921199-B9D1-4BF3-8880-9F2AE0787DCAQ24805040-650662F4-6AE2-4DBA-A878-06C65A1BF2E2Q28540528-03DB0CAC-85F7-4510-B5DA-6F2C5E3532B4Q33352443-D7070AB9-9715-4A7E-817B-DB80F637A4FAQ33511677-57825037-FA02-4227-ABE8-DB5F11B16FF5Q33549689-48C81295-B941-485F-AEBD-7DD163FA4174Q33641541-4E651B79-EC07-4CAC-B23B-5A01AA10DA76Q33658578-ED3493BC-943A-46D8-835A-BD86E680E6F9Q33771080-6C5BBBB7-6968-4260-A9CF-62E185D8374AQ33829414-F29415E7-6AD2-4646-B61B-F721C4E1E5B8Q33898617-C639DC9D-2BCC-49A4-8319-FCDA9AF8DA2BQ34042332-47BBF725-E729-4CDF-9F51-378006DB0688Q34113318-D924208E-8B48-470E-993F-D582CF0B35A3Q34324645-9EF71451-A00E-42E0-93E2-6835E819F03AQ34349607-B7E756D2-F9C2-4D60-B890-CEF0FC158978Q34354361-13ACF52F-8E55-48B4-91B6-B637A15BC2E4Q34429109-31183B51-0CD6-466E-BACF-282ED5B39376Q34552005-2055F04A-0239-4751-B008-3E1016F67226Q34838428-9B3B5B78-D4A6-4B2D-A2C2-79AD48A1E41AQ35097421-BC3509BF-8505-48D6-AE16-D003A3A1760FQ35345071-8E620851-5ACC-41A2-BEB8-216B8A75406AQ35620470-0275FE58-BE42-4330-8CBC-BC0BCD1E5DD9Q35828629-52BAEFA0-47F5-4536-854D-B06923613010Q35881172-B03066A7-BF15-49EB-A96F-9E214B367097Q35892881-B9D3F936-470F-4F38-BA88-8C180FBF53DFQ35925121-FAEBB6F4-08BE-471B-87FA-4F91A45AF5C3Q36410444-CA4D0755-2A04-4FEB-8558-D241D67C06FEQ36414044-4E9EEBAB-CBAF-4C24-A5B9-51D528A16408Q36535617-E6C623E4-2BC3-4126-B232-55062763E7B9Q36689662-98ED1640-2F03-417E-8D0E-2D7478D5CC2CQ36897356-A7260B48-54ED-4CB8-89D7-BADAE66AB28CQ37119601-74073B7D-8DC1-4249-9AEC-017B3594A41BQ37164254-10707AC5-8BF2-47AB-96A1-01412F829213Q37306391-B9681149-AB05-420D-89A1-2A1EAE253024Q37338010-CA1DE28D-E63F-4F88-B347-8EBD7935B525Q38307626-A35D954B-7233-41E7-A037-7902E0E1C5FF
P2860
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@ast
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@en
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@nl
type
label
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@ast
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@en
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@nl
prefLabel
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@ast
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@en
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@nl
P2093
P2860
P356
P1476
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
@en
P2093
Long H Dang
Timothy A Chan
Zhenghe Wang
P2860
P304
P356
10.1073/PNAS.082240999
P407
P4510
P577
2002-06-01T00:00:00Z